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CD32B

Fc fragment of IgG, low affinity IIb, receptor (CD32)

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Gene Name: Fc fragment of IgG, low affinity IIb, receptor (CD32)
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: FCGR2B, CD32, CD32 antigen, CD32B, CDw32, FCG2, FcRII-b, IgG Fc receptor II-b, Fc gamma RIIb, Fc-gamma RII-b, FCGR2, Fc-gamma-RIIb, IGFR2
Target Sequences: NM_004001 NP_003992.3 P31994

Publications (1)

1
Peripheral formalin injection induces unique spinal cord microglial phenotypic changes. Fu KY, Tan YH, Sung B, Mao J. Neuroscience letters. 2009 449:234-9. (IHC) [PubMed:19015000]

☰ Filters
Products
Antibodies (55)
Primary (55)
CD32B (55)
Human (36)
Mouse (12)
Rat (8)
Chimpanzee (3)
Crab-eating macaque (8)
Cynomolgus (4)
Gibbon (6)
Monkey (5)
IHC (10)
IHC-Fr (1)
IHC-P (11)
WB (29)
Flo (10)
ELISA (26)
IF (3)
IP (1)
Peptide-ELISA (3)
rabbit (43)
mouse (10)
goat (1)
rat (1)
Product Group
IHCPlus (2)
IgG (23)
IgG1 (7)
IgG2b (1)
monoclonal mc (15)
polyclonal pc (40)
005 (1)
01 (1)
046 (3)
06 (1)
12 (4)
AT130-5 (2)
AT130-5R (1)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (7)
HRP Conjugated (4)
PE Conjugated (3)
Preservative Free (6)
Unconjugated (34)
C-Terminus (9)
aa250-279 (7)
pTyr292 (3)
aa298-310 (1)
p292 (1)
No (55)
CD32B Antibody - Anti-CD32B antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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CD32B Goat anti-Human Polyclonal (aa298-310) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
CD32B Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD32B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD32B Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD32B Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
CD32B Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD32B Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
CD32B Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD32B Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
CD32B Antibody - Immunohistochemical analysis of CD32b staining in human lymph node formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CD32B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$321
CD32B Antibody - FCGR2B / CD32B antibody Western blot of Fetal Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD32B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
CD32B Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CD32B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CD32B Rabbit anti-Cynomolgus Polyclonal Antibody
Cynomolgus
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
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CD32B Mouse anti-Cynomolgus Monoclonal Antibody
Cynomolgus
ELISA
Unconjugated
100 µl/$412
CD32B Antibody - Western blot analysis of CD32b (pY292) expression in MCF7 pervanadate-treated (A); mouse liver (B); PC12 pervanadate-treated (C) whole cell lysates.
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CD32B Rabbit anti-Human Polyclonal (pTyr292) Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
100 µl/$315
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CD32B Rabbit anti-Cynomolgus Polyclonal Antibody
Cynomolgus
ELISA
Unconjugated
100 µl/$412
CD32B Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution of 1:100
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CD32B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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CD32B Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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CD32B Mouse anti-Mouse Monoclonal (FITC) (AT130-5) Antibody
Mouse
Flo
FITC Conjugated
0.1 mg/$432
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CD32B Rabbit anti-Mouse Monoclonal (Preservative Free) (005) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
100 µl/$412
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CD32B Rabbit anti-Human Polyclonal (pTyr292) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$328; 100 µl/$419
CD32B Antibody - Flow cytometric analysis of Cynomolgus CD32 expression on Cynomolgus monocytes. Cells were stained with APC-conjugated anti-CD32. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
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CD32B Rabbit anti-Crab-eating macaque Monoclonal (APC) (046) Antibody
Crab-eating macaque
Flo
APC Conjugated
25 Tests/$293; 100 Tests/$376
CD32B Antibody - Flow cytometric analysis of Cynomolgus CD32 expression on Cynomolgus monocytes. Cells were stained with FITC-conjugated anti-CD32. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
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CD32B Rabbit anti-Crab-eating macaque Monoclonal (FITC) (046) Antibody
Crab-eating macaque
Flo
FITC Conjugated
25 Tests/$278; 100 Tests/$346
CD32B Antibody - Flow cytometric analysis of Cynomolgus CD32 expression on Cynomolgus monocytes. Cells were stained with PE-conjugated anti-CD32. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
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CD32B Rabbit anti-Crab-eating macaque Monoclonal (PE) (046) Antibody
Crab-eating macaque
Flo
PE Conjugated
25 Tests/$293; 100 Tests/$376
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CD32B Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
20 µl/$271; 100 µl/$412
CD32B Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
CD32B Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
CD32B Rabbit anti-Rat Polyclonal Antibody
Rat
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
Select
CD32B Rabbit anti-Human Polyclonal (aa250-279) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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CD32B Rabbit anti-Human Polyclonal (aa250-279) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).