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CD30

tumor necrosis factor receptor superfamily, member 8

CD30 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene Name: tumor necrosis factor receptor superfamily, member 8
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF8, CD30L receptor, CD30, Cytokine receptor CD30, D1S166E, Ki-1, Ki-1 antigen, CD30 antigen
Target Sequences: NM_001243 NP_001234.3 P28908

Publications (1)

1
Activity of the growth hormone-releasing hormone antagonist MIA602 and its underlying mechanisms of action in sarcoidosis-like granuloma. Chongxu Zhang, Runxia Tian, Emilee M Dreifus, Abdolrazagh Hashemi Shahraki, Gregory Holt, Renzhi Cai, Anthony Griswold, Pablo Bejarano, Robert Jackson, Andrew V Schally, Mehdi Mirsaeidi. Clinical and Translational Immunology. 2021 July;10:e1310. [Full Text Article] [PubMed:34257968] [PMC:PMC8256670] Related Antibodies: LS-C162069.

☰ Filters
Products
Proteins (16)
Over-Expression Lysate (2)
Recombinant (14)
CD30 (16)
Bind (1)
ELISA (1)
Func (1)
SDS-PAGE (2)
No (16)
6His, C-terminus (2)
DDK,C-terminus (1)
Fc, C-terminus (2)
GST, N-terminus (1)
His (1)
His,C-terminus (4)
His-AVI, C-terminus (1)
Mouse IgG Fc, C-terminus (1)
Myc-DDK (Flag) (3)
Human (12)
Mouse (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (5)
Human (1)
Human Cells (2)
Mammalian Cells (4)
Sf9 Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (10)
Biologically active (1)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
28.4kD
10 µg/$248; 50 µg/$288; 500 µg/$725; 1 mg/$1,113
CD30 Protein - Purified recombinant protein TNFRSF8 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
61.9 kDa
20 µg/$1,107
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
40 kDa
100 µg/$502
CD30 Protein
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse TNFRSF8 consists of 251 amino acids and predicts a molecular mass of 26.6 kDa.
100 µg/$403; 1 mg/$1,697
CD30 Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
CD30 Protein - Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD30 at 2 µg/ml (100 µl/well) can bind human CD30L Fc Chimera with a linear range of 6.4-800 ng/ml.
Select
HEK 293 Cells
His,C-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The secreted recombinant human TNFRSF8 consists of 372 amino acids and has a predicted molecular mass of 40 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhTNFRSF8 is approximately 75-90 kDa due to glycosylation.
100 µg/$403; 1 mg/$1,697
CD30 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
293T Cells
Myc-DDK (Flag)
63.75 kDa
20 µg/$215
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
65.2kD
10 µg/$258; 50 µg/$321; 500 µg/$1,262; 1 mg/$1,627
Select
HEK 293 Cells
Myc-DDK (Flag)
63.75 kDa
100 µg/$710
CD30 Protein
Select
Sf9 Cells
DDK,C-terminus
40.4 kDa
20 µg/$677
CD30 Protein - Recombinant Human TNFRSF8/CD30L Receptor/CD30 (C-mFc)
Select
Human
Mouse IgG Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
64.8 kDa
10 µg/$265; 50 µg/$373
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
65.2 kDa
10 µg/$259; 50 µg/$317
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
28.4 kDa
10 µg/$248; 50 µg/$288
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
39.2 kDa
10 µg/$277; 50 µg/$389
Select
Mammalian Cells
His-AVI, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
41.1 kDa
20 µg/$416; 100 µg/$910
Viewing 1-16 of 16 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).