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CD24

CD24 molecule

CD24 is a sialoglycoprotein that is expressed on mature granulocytes and B cells and modulates growth and differentiation signals to these cells. The precursor protein is cleaved to a short 32 amino acid mature peptide which is anchored via a glycosyl phosphatidylinositol (GPI) link to the cell surface. This gene was missing from previous genome assemblies, but is properly located on chromosome 6. Non-transcribed pseudogenes have been designated on chromosomes 1, 15, 20, and Y. Alternative splicing results in multiple transcript variants.

Gene Name: CD24 molecule
Synonyms: CD24, CD24 molecule, CD24A, Signal transducer CD24, CD24 antigen
Target Sequences: NM_013230 NP_037362.1

Publications (4)

1
Optical imaging detection of microscopic mammary cancer in ErbB-2 transgenic mice through the DA364 probe binding av ß3 integrins. Conti L, Lanzardo S, Iezzi M, Montone M, Bolli E, Brioschi C, Maiocchi A, Forni G, Cavallo F. Contrast media & molecular imaging. 2013 July;8:350-60. [Full Text Article] [PubMed:23613438]
2
TGF-ß1 and GDF5 Act Synergistically to Drive the Differentiation of Human Adipose Stromal Cells toward Nucleus Pulposus-like Cells. Colombier P, Clouet J, Boyer C, Ruel M, Bonin G, Lesoeur J, Moreau A, Fellah BH, Weiss P, Lescaudron L, Camus A, Guicheux J. Stem cells (Dayton, Ohio). 2016 March;34:653-67. [Full Text Article] [PubMed:26661057]
3
CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model. Katrin Kleinmanns, Vibeke Fosse, Ben Davidson, Elvira García de Jalón, Olav Tenstad, Line Bjørge, Emmet McCormack. EBioMedicine. 2020 Jun;56:102783. [Full Text Article] [PubMed:32454402] [PMC:PMC7248677]
4
Hyperosmolar expansion medium improves nucleus pulposus cell phenotype. Lisanne T Laagland, Frances C Bach, Laura B Creemers, Christine L Le Maitre, Deepani W Poramba-Liyanage, Marianna A Tryfonidou. JOR spine. 2022 September;5:e1219. [Full Text Article] [PubMed:36203869] [PMC:PMC9520765]
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Products
Proteins (15)
Recombinant (15)
CD24 (15)
No (15)
Fc (2)
Fc, C-terminus (4)
Fc-AVI, C-terminus (1)
GST (3)
GST, N-terminus + His, C-terminus (1)
His-GST (1)
Human IgG1 Fc, C-terminus (1)
Mouse IgG Fc, C-terminus (1)
Human (11)
Mouse (3)
Rat (1)
E. coli (3)
HEK 293 Cells (2)
Human (5)
Human Cells (2)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (6)
Low endotoxin level (10)
Biologically active (3)
Select
E. coli
GST
32.7 kD
20 µg/$323; 1 mg/$1,355; 100 µg/$420
Select
HEK 293 Cells
Human IgG1 Fc, C-terminus
Less than 0.06 EU/µg protein (determined by LAL method).
~40 kDa (SDS-PAGE)
50 µg/$456
Select
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
29.9 kDa
100 µg/$721
CD24 Protein - Recombinant Mouse Signal Transducer CD24/CD24 (C-Fc)
Select
Human
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
29.6 kDa
10 µg/$290; 50 µg/$446
CD24 Protein
Select
E. coli
GST, N-terminus + His, C-terminus
34.1 kDa
50 µg/$419
CD24 Protein - Recombinant Human Signal Transducer CD24/CD24 (C-mFC)
Select
Human
Mouse IgG Fc, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
29.5 kDa
10 µg/$290; 50 µg/$446
CD24 Protein - Recombinant Human Signal Transducer CD24/CD24 (C-Fc)
Select
Human
Fc, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
29.8 kDa
10 µg/$290; 50 µg/$446
CD24 Protein - Recombinant Human Signal Transducer CD24/CD24 (C-Fc-Avi) Biotinylated
Select
Human
Fc-AVI, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
31.6 kDa
20 µg/$416; 100 µg/$910
CD24 Protein - 12.5% SDS-PAGE of human CD24 stained with Coomassie Blue
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Wheat Germ Extract
GST
31.57 kDa
10 µg/$479; 25 µg/$670
CD24 Protein - 12.5% SDS-PAGE of human CD24 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
34.54 kDa
10 µg/$479; 25 µg/$670
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
30 kDa
100 µg/$721
Select
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
29.7 kDa
100 µg/$721
Select
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
29.8 kDa
10 µg/$266; 50 µg/$371
Select
Human
None
Less than 1.0 EU/µg protein (determined by LAL method).
29.8kD
10 µg/$266; 50 µg/$376; 500 µg/$1,067; 1 mg/$1,369
CD24 Protein - Recombinant Cluster Of Differentiation 24 By SDS-PAGE
Select
E. coli
His-GST
37.3 kDa
10 µg/$265; 50 µg/$347; 100 µg/$545; 200 µg/$682; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).