CD22

CD22 molecule

Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

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Products

Proteins (12)

Type

Over-Expression Lysate (2)

Recombinant (10)

Target

CD22 (12)

Publications

No (12)

Tag

6His, C-terminus (1)

AVI-6His, C-terminus (1)

Fc (1)

Fc, C-terminus (1)

His (2)

His,C-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (8)

Mouse (3)

Source

293T Cells (1)

CHO Cells (1)

E. coli (1)

HEK 293 Cells (3)

Human (2)

Human Cells (2)

Mammalian Cells (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (8)

Biologically Active

Biologically active (1)

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Human CD22 Protein (Recombinant) - LS-G10

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

75.0 kDa

Price:

5 µg/$268; 20 µg/$349

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Human CD22 Protein (Recombinant His) (aa28-246) - LS-G13409

Source:

E. coli

Tag:

His

Molecular Weight:

26.7 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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Human CD22 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65033

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

95.2 kDa

Price:

20 µg/$1,107

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Mouse CD22 Protein (Recombinant His) (Met1-Arg708) - LS-G98081

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

78.8 kDa

Price:

100 µg/$721

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Mouse CD22 Protein (Recombinant Fc) (Met1-Arg708) - LS-G98082

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

104.3 kDa

Price:

100 µg/$721

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Human CD22 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74688

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

76.2 kDa

Price:

20 µg/$215

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Human CD22 Protein (Recombinant AVI-6His, C-terminus) - LS-G146095

Source:

Human

Tag:

AVI-6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

78 kDa

Price:

20 µg/$416; 100 µg/$910

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Mouse CD22 Protein (Recombinant 6His, C-terminus) - LS-G146268

Source:

Human

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

77.3 kDa

Price:

10 µg/$276; 50 µg/$405

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Human CD22 Protein (Recombinant Fc, C-terminus) (Asp20-Arg687) - LS-G139831

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

102.3 kDa

Price:

10 µg/$288; 50 µg/$436

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Human CD22 Protein (Recombinant His,C-terminus) (Asp20-Arg687) - LS-G139832

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

76.2 kDa

Price:

10 µg/$288; 50 µg/$436

Select

CD22 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G131082

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

76.2 kDa

Price:

100 µg/$710

Select

Human CD22 Protein (Recombinant His,C-terminus) (Trp176-Arg687) - LS-G138015

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

58.5 kDa

Price:

100 µg/$721

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