CD207 / Langerin

CD207 molecule, langerin

Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

CD207 / Langerin (8)

Publications

No (8)

Tag

6His, N-terminus (2)

GST (1)

His (1)

His,N-terminus (1)

Myc-DDK (Flag) (2)

Myc-DDK (Flag), C-terminus (1)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Human (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

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Mouse CD207 / Langerin Protein (Recombinant 6His, N-terminus) (aa63-331) - LS-G56846

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human CD207 / Langerin Protein (Recombinant 6His, N-terminus) (Tyr64-Pro328) - LS-G55775

Source:

Human

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

31.5kD

Price:

50 µg/$395; 500 µg/$1,585; 1 mg/$2,157; 10 µg/$281

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Human CD207 / Langerin Protein (Recombinant His) - LS-G3260

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human CD207 / Langerin Protein (Recombinant Myc-DDK (Flag), C-terminus) (Full Length) - LS-G71592

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag), C-terminus

Molecular Weight:

36.5 kDa

Price:

20 µg/$1,107

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Human CD207 / Langerin Protein (Recombinant GST) (Full Length) - LS-G33536

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.82 kDa

Price:

10 µg/$479; 25 µg/$670

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CD207 / Langerin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101345

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.5 kDa

Price:

100 µg/$494

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Human CD207 / Langerin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90161

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.5 kDa

Price:

20 µg/$150

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Human CD207 / Langerin Protein (Recombinant His,N-terminus) (Tyr64-Pro328) - LS-G139359

Source:

Mammalian Cells

Tag:

His,N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

31.5 kDa

Price:

10 µg/$281; 50 µg/$389

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