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CD20 is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This gene encodes a B-lymphocyte surface molecule which plays a role in the development and differentiation of B-cells into plasma cells. This family member is localized to 11q12, among a cluster of family members. Alternative splicing of this gene results in two transcript variants which encode the same protein.
Gene Name: | membrane-spanning 4-domains, subfamily A, member 1 |
Synonyms: | MS4A1, B-lymphocyte antigen CD20, B1, Bp35, CD20, CD20 antigen, CD20 receptor, LEU-16, CVID5 |
Target Sequences: | NM_021950 NP_690605.1 P11836 |
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