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CD1D

CD1d molecule

CD1D is a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail.

Gene Name: CD1d molecule
Synonyms: CD1D, CD1D antigen, d polypeptide, R3, R3G1, CD1d antigen, CD1d molecule, Thymocyte antigen CD1D
Target Sequences: NM_001766 NP_001757.1 P15813

Publications (1)

1
Increased cytoplasmatic expression of cancer immune surveillance receptor CD1d in anaplastic thyroid carcinomas. Weber F, Junger H, Werner JM, Velez Char N, Rejas C, Schlitt HJ, Hornung M. Cancer medicine. 2019 November;8:7065-7073. [Full Text Article] [PubMed:31560833] [PMC:PMC6853836]

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Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
CD1D (9)
No (9)
Fc, C-terminus (1)
GST (1)
His (1)
His-SUMO (1)
His-T7 (3)
Myc-DDK (Flag) (2)
Human (5)
Mouse (2)
Rat (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Human Cells (1)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (1)
CD1D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
37.72 kDa
100 µg/$494
CD1D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
37.72 kDa
20 µg/$150
CD1D Protein
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E. coli
His-SUMO
47.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CD1D Protein - 12.5% SDS-PAGE of human CD1D stained with Coomassie Blue
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Wheat Germ Extract
GST
62.59 kDa
2 µg/$439
CD1D Protein - Recombinant Cluster Of Differentiation 1d By SDS-PAGE
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E. coli
His-T7
30.1 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
CD1D Protein - Recombinant Cluster Of Differentiation 1d By SDS-PAGE
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E. coli
His-T7
34.7 kDa
10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278
CD1D Protein - Recombinant Cluster Of Differentiation 1d By SDS-PAGE
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E. coli
His-T7
28.5 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
CD1D Protein
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HEK 293 Cells
Fc, C-terminus
59 kDa
20 µg/$1,107
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Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
33.7 kDa
100 µg/$721
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).