CD163

CD163 molecule

Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.After shedding, the soluble form (sCD163) may play an anti-inflammatory role, and may be a valuable diagnostic parameter for monitoring macrophage activation in inflammatory conditions.

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Antibodies (123)

ELISA Kits (26)

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Custom (4)

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Sandwich CLIA (2)

Target

CD163 (158)

Reactivity

Human (95)

Mouse (24)

Rat (23)

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monoclonal mc (79)

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Low Endotoxin Level

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IHC-plus™ CD163 Antibody (N-Terminus) LS-B2661

(5.0) Rating

(1) Publication(s)

Antibody:

CD163 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

125 µl/$460

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PathPlus™ CD163 Antibody (clone ED2) LS-B5967

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

CD163 Mouse anti-Rat Monoclonal (ED2) Antibody

Reactivity:

Rat

Applications:

Flo, IHC, IHC-Fr, IHC-P, IP

Format:

Unconjugated

Price:

100 µg/$655

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IHC-plus™ CD163 Antibody (clone 3B4) LS-B10966

(4.0) Rating

Antibody:

CD163 Mouse anti-Human Monoclonal (3B4) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ CD163 Antibody (clone 2F8) LS-B12939

(4.0) Rating

Antibody:

CD163 Mouse anti-Human Monoclonal (2F8) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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PathPlus™ CD163 Antibody (clone GHI/61) LS-B3781

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

CD163 Mouse anti-Human Monoclonal (GHI/61) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ CD163 Antibody (clone MRQ-26) LS-B7224

(4.0) Rating

Antibody:

CD163 Mouse anti-Human Monoclonal (MRQ-26) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.25 ml/$785

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CD163 Antibody (clone 2A10/11) LS-C187487

Antibody:

CD163 Mouse anti-Pig Monoclonal (2A10/11) Antibody

Reactivity:

Pig

Applications:

Flo, IF, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$457

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CD163 Antibody (clone 2A10/11) LS-C123173

Antibody:

CD163 Mouse anti-Pig Monoclonal (2A10/11) Antibody

Reactivity:

Pig

Applications:

Flo, IHC, IHC-Fr, IP, WB

Format:

Unconjugated

Price:

100 µg/$725

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CD163 Antibody (clone ED2) LS-C188455

Antibody:

CD163 Mouse anti-Rat Monoclonal (ED2) Antibody

Reactivity:

Rat

Applications:

IF, IHC, IHC-Fr, IHC-P, IP, WB

Format:

Unconjugated

Price:

0.1 mg/$479

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CD163 Antibody (clone MRQ-26, Concentrated) LS-C202817

Antibody:

CD163 Mouse anti-Human Monoclonal (Concentrated) (MRQ-26) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated, Concentrated

Price:

1 ml/$1,207

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CD163 Antibody (aa697-972) LS-C293343

Antibody:

CD163 Rabbit anti-Mouse Polyclonal (aa697-972) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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IHC-plus™ CD163 Antibody (clone 2B12) LS-B11895

(4.0) Rating

Antibody:

CD163 Mouse anti-Human Monoclonal (2B12) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ CD163 Antibody (clone 3D4) LS-B14153

(4.0) Rating

Antibody:

CD163 Mouse anti-Human Monoclonal (3D4) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ CD163 Antibody LS-B15360

(4.0) Rating

Antibody:

CD163 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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CD163 Antibody (aa245-274) LS-C100918

Antibody:

CD163 Rabbit anti-Human Polyclonal (aa245-274) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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Mouse CD163 (Sandwich ELISA) ELISA Kit - LS-F2855

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

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Mouse CD163 (Sandwich ELISA) ELISA Kit - LS-F9079

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$715

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Rat CD163 (Sandwich ELISA) ELISA Kit - LS-F9679

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

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CD163 Antibody LS-C285807

Antibody:

CD163 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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Rat CD163 Protein (Recombinant His) (aa693-939) - LS-G24444

Source:

E. coli

Tag:

His

Molecular Weight:

28.3 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Monkey CD163 (Sandwich ELISA) ELISA Kit - LS-F32525

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

Select

CD163 Antibody (clone ED2) LS-C96399

(4.0) Rating

(1) Publication(s)

Antibody:

CD163 Mouse anti-Rat Monoclonal (ED2) Antibody

Reactivity:

Rat

Applications:

IHC, IHC-Fr, IHC-P

Format:

Unconjugated

Price:

250 µg/$752

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PathPlus™ CD163 Antibody (clone 1B4) LS-B10014

Cancer Pathology

Cancer

(5.0) Rating

Antibody:

CD163 Mouse anti-Human Monoclonal (1B4) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$440

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CD163 Antibody (clone OTI1D5) LS-C338099

Antibody:

CD163 Mouse anti-Human Monoclonal (OTI1D5) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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CD163 Antibody (clone OTI1H1) LS-C338100

Antibody:

CD163 Mouse anti-Human Monoclonal (OTI1H1) Antibody

Reactivity:

Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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