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CD14
CD14 molecule
In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
| Gene Name: | CD14 molecule |
| Synonyms: | CD14, CD14 molecule, CD14 antigen |
| Target Sequences: | NM_000591 NP_000582.1 P08571 |
Publications (11)
1
TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses. Iwamoto S, Iwai S, Tsujiyama K, Kurahashi C, Takeshita K, Naoe M, Masunaga A, Ogawa Y, Oguchi K, Miyazaki A. Journal of immunology (Baltimore, Md. : 1950). 2007 179:1449-57.
[PubMed:17641010]
Related Antibodies: LS-C41087.
2
C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes. Santer DM, Hall BE, George TC, Tangsombatvisit S, Liu CL, Arkwright PD, Elkon KB. Journal of immunology (Baltimore, Md. : 1950). 2010 185:4738-49.
[PubMed:20844193]
[PMC:PMC3065655]
Related Antibodies: LS-C41087.
3
LPS-induced TLR4 signaling in human colorectal cancer cells increases beta1 integrin-mediated cell adhesion and liver metastasis. Hsu RY, Chan CH, Spicer JD, Rousseau MC, Giannias B, Rousseau S, Ferri LE. Cancer research. 2011 71:1989-98. (IHC)
[PubMed:21363926]
☰ Filters
Products
ELISA Kits
(16)
Type
Custom
(3)
Development Kit
(1)
Sandwich
(12)
Target
CD14
(16)
Reactivity
Human
(7)
Mouse
(5)
Rat
(2)
Pig
(1)
Product Group
DevKit DuoPlus
(1)
Format
96-Well Microplate
(3)
96-Well Strip Plate
(11)
Antibody Pair and Standard
(1)
Publications
No
(15)
Yes
(1)
Sample Type
Cell Culture Supernatants
(5)
Cell Lysates
(2)
Citrate Plasma
(1)
EDTA Plasma
(1)
Heparin Plasma
(1)
Plasma
(12)
Serum
(13)
Tissue Homogenates
(5)
Urine
(1)
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
Sandwich
96-Well Strip Plate
Human
0.94 - 60 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$764
Sandwich
96-Well Strip Plate
Pig
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$779
Sandwich
96-Well Microplate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
Sandwich
96-Well Strip Plate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$624
Sandwich
96-Well Microplate
Human
8.23 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$426
Sandwich
96-Well Microplate
Human
0.234 - 15 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates, Urine
1 Plate/$744
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$585
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$585
Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
Human
156 - 10000 pg/ml
Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$699
Development Kit
Antibody Pair and Standard
Human
7.5 - 120 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
500 Wells/$1,041; 1000 Wells/$1,512
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