CD135 / FLT3

fms-related tyrosine kinase 3

Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

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Products

ELISA Kits (19)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (1)

Sandwich (15)

Target

CD135 / FLT3 (19)

Reactivity

Human (9)

Mouse (5)

Chicken (1)

Guinea pig (1)

Monkey (1)

Pig (1)

Rabbit (2)

Sheep (1)

Format

96-Well Microplate (5)

96-Well Strip Plate (13)

Publications

No (19)

Sample Type

Adherent Cell Cultures (3)

Cell Culture Supernatants (1)

Cell Lysates (1)

EDTA Plasma (1)

Heparin Plasma (1)

Lysates (1)

Plasma (8)

Serum (9)

Tissue (1)

Tissue Homogenates (5)

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Human CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F22004

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F32088

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F51910

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$758

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Mouse/Human Phospho-CD135 / FLT3 (Tyr842) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1680

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Human Phospho-CD135 / FLT3 (Tyr969) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1681

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human CD135 / FLT3 (Cell-Based ELISA) ELISA Kit - LS-F1995

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

Select

Human CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F4003

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

Select

Human CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F11478

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

Guinea pig CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F44018

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Chicken CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F44017

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F44019

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Rabbit CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F44020

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Sheep CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F44021

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

Select

Human CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F57092

Type:

Sandwich

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Lysates, Serum, Tissue

Price:

1 Plate/$699

Select

Mouse CD135 / FLT3 (Custom ELISA) ELISA Kit - LS-F13606

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$585

Select

Human CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F35532

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rabbit CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F32238

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Pig CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F23281

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Pig

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse CD135 / FLT3 (Sandwich ELISA) ELISA Kit - LS-F38322

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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