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CD105
endoglin
CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | endoglin |
| Synonyms: | ENG, CD105, CD105 antigen, END, HHT1, ORW, ORW1, Osler-Rendu-Weber syndrome 1, Endoglin |
| Target Sequences: | NM_000118 NP_000109.1 P17813 |
Publications (2)
1
Differential expression of CD44 and CD24 markers discriminates the epitheliod from the fibroblastoid subset in a sarcomatoid renal carcinoma cell line: evidence suggesting the existence of cancer stem cells in both subsets as studied with sorted cells. Hsieh CH, Hsiung SC, Yeh CT, Yen CF, Chou YW, Lei WY, Pang ST, Chuang CK, Liao SK. Oncotarget. 2017 8:15593-15609. (WB; Human)
[Full Text Article]
[PubMed:28121626]
[PMC:PMC5362508]
2
Angiogenic response in an in vitro model of dog microvascular endothelial cells stimulated with antigenic extracts from Dirofilaria immitis adult worms. Tatiana Zueva, Rodrigo Morchón, Elena Carretón, José Alberto Montoya-Alonso, Alexis Santana, María Dolores Bargues, Santiago Mas-Coma, Alicia Rodríguez-Barbero, Fernando Simón. Parasites & vectors. 2019 June;12:315. [Full Text Article]
[PubMed:31234915]
[PMC:PMC6591997]
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Antibodies
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Type
Primary
(222)
Target
CD105
(222)
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(179)
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(57)
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(23)
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(164)
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(222)
Cancer
CD105 Mouse anti-Human Monoclonal (8A1) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD105 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD105 Rabbit anti-Human Polyclonal (aa380-409) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CD105 Mouse anti-Human Monoclonal (PE) (MEM-229) Antibody
Porcine, Human
Flo, ICC, IHC-Fr, WB
PE Conjugated
100 Tests/$365
CD105 Mouse anti-Human Monoclonal (FITC) (MEM-229) Antibody
Porcine, Human
Flo
FITC Conjugated
100 Tests/$337
CD105 Mouse anti-Human Monoclonal (3A9) Antibody
Human
ELISA, Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
CD105 Mouse anti-Human Monoclonal (3A9) Antibody
Human
Flo, ICC, IF, IHC-P, WB
Unconjugated
100 µl/$503
CD105 Mouse anti-Human Monoclonal (Carrier-free) (8A1) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, WB
Unconjugated, Carrier-free
100 µg/$511
CD105 Mouse anti-Human Monoclonal (FITC) (SN6) Antibody
Horse, Human
Flo, ICC, IHC-Fr, IHC-P, IP, Purif, WB
FITC Conjugated
100 Tests/$369
CD105 Mouse anti-Human Monoclonal (APC) (SN6) Antibody
Horse, Human
Flo, ICC, IHC-Fr, IHC-P, IP, Purif, WB
APC Conjugated
100 Tests/$418
CD105 Rabbit anti-Human Polyclonal (N-term) (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
CD105 Mouse anti-Human Monoclonal (MEM-229) Antibody
Porcine, Human
Flo, ICC, IHC, IHC-Fr, WB
Unconjugated
0.1 mg/$309
CD105 Mouse anti-Human Monoclonal (OTI3H5) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
CD105 Mouse anti-Human Monoclonal (SN6) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
25 µg/$281; 0.2 mg/$471
CD105 Rabbit anti-Human Polyclonal (aa380-409) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
CD105 Rabbit anti-Human Polyclonal (aa380-409) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CD105 Rabbit anti-Mouse Monoclonal (Preservative Free) (001) Antibody
Mouse
ELISA, Flo, WB
Unconjugated, Preservative Free
100 µl/$412
CD105 Mouse anti-Human Monoclonal (Extracellular Domain) Antibody
Human
Flo, ICC
Unconjugated
100 µg/$884
CD105 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IHC-Fr
FITC Conjugated
120 Tests/$626
CD105 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
CD105 Mouse anti-Human Monoclonal (Biotin) (SN6/N1-3A1) Antibody
Human
Flo, IHC
Biotin Conjugated
100 µg/$446
CD105 Mouse anti-Human Monoclonal (3A9) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
CD105 Rabbit anti-Mouse Polyclonal (aa27-137) Antibody
Mouse
WB
Unconjugated
100 µl/$273; 200 µl/$299; 500 µl/$388; 1 ml/$433; 2 ml/$521; 5 ml/$876
CD105 Rabbit anti-Mouse Monoclonal (Preservative Free) (029) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
CD105 Rabbit anti-Mouse Monoclonal (Preservative Free) (028) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
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