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CD105

endoglin

CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: endoglin
Synonyms: ENG, CD105, CD105 antigen, END, HHT1, ORW, ORW1, Osler-Rendu-Weber syndrome 1, Endoglin
Target Sequences: NM_000118 NP_000109.1 P17813

Publications (2)

1
Differential expression of CD44 and CD24 markers discriminates the epitheliod from the fibroblastoid subset in a sarcomatoid renal carcinoma cell line: evidence suggesting the existence of cancer stem cells in both subsets as studied with sorted cells. Hsieh CH, Hsiung SC, Yeh CT, Yen CF, Chou YW, Lei WY, Pang ST, Chuang CK, Liao SK. Oncotarget. 2017 8:15593-15609. (WB; Human) [Full Text Article] [PubMed:28121626] [PMC:PMC5362508]
2
Angiogenic response in an in vitro model of dog microvascular endothelial cells stimulated with antigenic extracts from Dirofilaria immitis adult worms. Tatiana Zueva, Rodrigo Morchón, Elena Carretón, José Alberto Montoya-Alonso, Alexis Santana, María Dolores Bargues, Santiago Mas-Coma, Alicia Rodríguez-Barbero, Fernando Simón. Parasites & vectors. 2019 June;12:315. [Full Text Article] [PubMed:31234915] [PMC:PMC6591997]

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CD105 Antibody - Anti-CD105 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer
CD105 Mouse anti-Human Monoclonal (8A1) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD105 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD105 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CD105 Antibody - CD105 antibody (Center E395) immunohistochemistry of formalin-fixed and paraffin-embedded mouse heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the CD105 antibody (Center E395) for immunohistochemistry.
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CD105 Rabbit anti-Human Polyclonal (aa380-409) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CD105 Antibody - Surface staining of CD105 on Huvec cells with anti-CD105 (MEM-229) PE.
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CD105 Mouse anti-Human Monoclonal (PE) (MEM-229) Antibody
Porcine, Human
Flo, ICC, IHC-Fr, WB
PE Conjugated
100 Tests/$365
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CD105 Mouse anti-Human Monoclonal (FITC) (MEM-229) Antibody
Porcine, Human
Flo
FITC Conjugated
100 Tests/$337
CD105 Antibody - Immunohistochemistry-Paraffin: CD105 Antibody (3A9) - Immunohistochemical analysis of paraffin-embedded kidney cancer tissues (left) and stomach cancer tissues (right) using CD105 mouse mAb with DAB staining.
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CD105 Mouse anti-Human Monoclonal (3A9) Antibody
Human
ELISA, Flo, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
CD105 Antibody - CD105 Antibody in Immunohistochemistry (IHC) using FFPE kidney cancer and stomach cancer.
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CD105 Mouse anti-Human Monoclonal (3A9) Antibody
Human
Flo, ICC, IF, IHC-P, WB
Unconjugated
100 µl/$503
CD105 Antibody - Anti-CD105 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CD105 Mouse anti-Human Monoclonal (Carrier-free) (8A1) Antibody
Mouse, Dog, Rat, Human, Monkey
IF, WB
Unconjugated, Carrier-free
100 µg/$511
CD105 Antibody - Human histiocytic lymphoma cell line U-937 was stained with Mouse Anti-Human CD105-FITC.
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CD105 Mouse anti-Human Monoclonal (FITC) (SN6) Antibody
Horse, Human
Flo, ICC, IHC-Fr, IHC-P, IP, Purif, WB
FITC Conjugated
100 Tests/$369
CD105 Antibody - Human histiocytic lymphoma cell line U-937 was stained with Mouse Anti-Human CD105-APC.
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CD105 Mouse anti-Human Monoclonal (APC) (SN6) Antibody
Horse, Human
Flo, ICC, IHC-Fr, IHC-P, IP, Purif, WB
APC Conjugated
100 Tests/$418
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CD105 Rabbit anti-Human Polyclonal (N-term) (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
CD105 Antibody - Immunofluorescence staining of an infarcted porcine heart with anti-CD105 (MEM-229; green); cell nuclei stained with DAPI (blue).        Primary antibody dilution: 5 ug/ml.
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CD105 Mouse anti-Human Monoclonal (MEM-229) Antibody
Porcine, Human
Flo, ICC, IHC, IHC-Fr, WB
Unconjugated
0.1 mg/$309
CD105 Antibody - IHC of paraffin-embedded Human liver tissue using anti-ENG mouse monoclonal antibody.
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CD105 Mouse anti-Human Monoclonal (OTI3H5) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
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CD105 Mouse anti-Human Monoclonal (SN6) Antibody
Human
Flo, IHC, IHC-Fr, IP, WB
Unconjugated
25 µg/$281; 0.2 mg/$471
CD105 ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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CD105 Rabbit anti-Human Polyclonal (aa380-409) (FITC) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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CD105 Rabbit anti-Human Polyclonal (aa380-409) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CD105 Antibody - Anti-ENG rabbit monoclonal antibody at 1:500 dilution. Lane A: MCF7 Whole Cell Lysate. Lane B: Jurkat Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 70 kDa. Observed band size: 45 kDa.
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CD105 Rabbit anti-Mouse Monoclonal (Preservative Free) (001) Antibody
Mouse
ELISA, Flo, WB
Unconjugated, Preservative Free
100 µl/$412
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CD105 Mouse anti-Human Monoclonal (Extracellular Domain) Antibody
Human
Flo, ICC
Unconjugated
100 µg/$884
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CD105 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IHC-Fr
FITC Conjugated
120 Tests/$626
CD105 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded kidney cancer tissues (left) and stomach cancer tissues (right) with DAB staining using CD105 Monoclonal Antibody.
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CD105 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
CD105 Antibody - Flow cytometry of CD105 antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD105 Mouse anti-Human Monoclonal (Biotin) (SN6/N1-3A1) Antibody
Human
Flo, IHC
Biotin Conjugated
100 µg/$446
CD105 Antibody - IHC of paraffin-embedded kidney cancer tissues (left) and stomach cancer tissues (right) using CD105 mouse monoclonal antibody with DAB staining.
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CD105 Mouse anti-Human Monoclonal (3A9) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
CD105 Antibody - Western blot of recombinant CD105.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD105 Rabbit anti-Mouse Polyclonal (aa27-137) Antibody
Mouse
WB
Unconjugated
100 µl/$273; 200 µl/$299; 500 µl/$388; 1 ml/$433; 2 ml/$521; 5 ml/$876
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CD105 Rabbit anti-Mouse Monoclonal (Preservative Free) (029) Antibody
Mouse
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
Viewing 1-25 of 272 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).