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CCT2 / CCT Beta
chaperonin containing TCP1, subunit 2 (beta)
This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized.
| Gene Name: | chaperonin containing TCP1, subunit 2 (beta) |
| Synonyms: | CCT2, 99D8.1, CCT-beta, CCTB, PRO1633, TCP-1-beta, TCP1 Beta |
| Target Sequences: | NM_006431 NP_006422.1 P78371 |
Publications (3)
1
Targeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer. Carr AC, Khaled AS, Bassiouni R, Flores O, Nierenberg D, Bhatti H, Vishnubhotla P, Manuel JP, Santra S, Khaled AR. Oncotarget. 2017 8:110273-110288. (WB; Human)
[Full Text Article]
[PubMed:29299146]
Related Antibodies: LS-B4861.
2
Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis. Anne E Showalter , Ana C Martini , Daniel Nierenberg, Kristen Hosang, Naima Ahmed Fahmi, Priya Gopalan, Amr S Khaled, Wei Zhang, Annette R Khaled. Scientific reports. 2020 Jan;10:798. [Full Text Article]
[PubMed:31964905]
[PMC:PMC6972895]
Related Antibodies: LS-B4861.
3
Chaperonin containing TCP1 as a marker for identification of circulating tumor cells in blood. Amanda Cox, Ana Martini, Heba Ghozlan, Rebecca Moroose, Xiang Zhu, Eunkyung Lee, Amr S Khaled, Louis Barr, Carlos Alemany, Na'im Fanaian, Elizabeth Griffith, Ryan Sause, S A Litherland, Annette R Khaled. PloS one. 2022 June;17:e0264651. [Full Text Article]
[PubMed:35749519]
[PMC:PMC9232171]
Related Antibodies: LS-C649415.
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CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
CCT2 / CCT Beta Mouse anti-Human Monoclonal (F39 P7 F11) Antibody
Xenopus, Zebrafish, Pig, Horse, Rat, Hamster, Mouse, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µg/$460
CCT2 / CCT Beta Mouse anti-Human Monoclonal (5B5C4) Antibody
Mouse, Rat, Non-Human Primate, Human
Flo, ICC, IF, WB
Unconjugated
100 µl/$518
CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CCT2 / CCT Beta Mouse anti-Human Monoclonal (5B5C4) Antibody
Human
ELISA, Flo, IF, WB
Unconjugated
100 µl/$459
CCT2 / CCT Beta Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human, Monkey
ELISA, Flo, IF, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$294; 100 µl/$360
E. coli
His-S
56.4 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CCT2 / CCT Beta Mouse anti-Human Monoclonal (aa117-217) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$705
CCT2 / CCT Beta Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
CCT2 / CCT Beta Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
CCT2 / CCT Beta Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IF, WB
FITC Conjugated
100 µl/$904
CCT2 / CCT Beta Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IF, WB
PE Conjugated
100 µl/$904
CCT2 / CCT Beta Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
CCT2 / CCT Beta Rabbit anti-Human Polyclonal (aa1-488) Antibody
Mouse, Human
ICC, IP, WB
Unconjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352
CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCT2 / CCT Beta Rabbit anti-Human Polyclonal (aa325-375) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
CCT2 / CCT Beta Mouse anti-Human Monoclonal (5B5F5) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
CCT2 / CCT Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
100 µg/$575
CCT2 / CCT Beta Mouse anti-Frog Monoclonal (F39 P7 F11) Antibody
Frog, Rat, Mouse, Human
IHC, WB
Unconjugated
200 µg/$466
CCT2 / CCT Beta Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
CCT2 / CCT Beta Rabbit anti-Human Polyclonal (aa484-534) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
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