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Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (800) 227-6666
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Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
CCR8 / CD198
chemokine (C-C motif) receptor 8
CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region.
| Gene Name: | chemokine (C-C motif) receptor 8 |
| Family/Subfamily: | GPCR , Chemokine |
| Synonyms: | CCR8, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, CC-CKR-8, Chemokine (C-C) receptor 8, CDw198 antigen, CKRL1, CMKBR8, Chemokine receptor-like 1, CMKBRL2, CKR-L1, GPRCY6, TER1, C-C CKR-8, CC chemokine receptor 8, CC-chemokine receptor chemr1, CCR-8, CDw198, CY6, GPR-CY6, CD198 |
| Target Sequences: | NM_005201 NP_005192.1 P51685 |
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