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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

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CCR2

chemokine (C-C motif) receptor 2

CCR2, a Chemokine Receptor, is a regulator of monocyte/macrophage trafficking and is upregulated in response to inflammation. Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms. The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages. Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis (Boring et al., 1998) and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration. Two isoforms are produced by alternative splicing.

Gene Name: chemokine (C-C motif) receptor 2
Family/Subfamily: GPCR , Chemokine
Synonyms: CCR2, C-C chemokine receptor type 2, CD192, Cc chemokine receptor 2, CCR-2, CCR2A, C-C CKR-2, CKR2, CD192 antigen, CKR2A, CKR2B, Mcp1 receptor, MCP-1 receptor, MCP-1-R, C-c chemokine receptor 2, CC-CKR-2, Cc-ckr2, CCR2B, CMKBR2, Mcp1r
Target Sequences: NP_001116868.1 P41597

Publications (1)

1
Interleukin-17 potently increases non-small cell lung cancer growth. Wei L, Wang H, Yang F, Ding Q, Zhao J. Molecular medicine reports. 2016 13:1673-80. (Flo; Mouse) [Full Text Article] [PubMed:26708832] Related Antibodies: LS-C127284.

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CCR2 ELISA Kit
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0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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1 Plate/$764
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78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
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1 Plate/$669
CCR2 ELISA Kit
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Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
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1 Plate/$782
CCR2 ELISA Kit
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Sandwich
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Human
23.44 - 1500 pg/ml
Colorimetric - 450nm (TMB)
Cerebrospinal Fluid, Plasma, Serum, Tissue Homogenates
1 Plate/$968
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Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
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1 Plate/$579
CCR2 ELISA Kit
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Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$897
CCR2 ELISA Kit
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96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$897
CCR2 ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
CCR2 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
CCR2 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).