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Cyclin L (also referred to as CCNL) is encoded by two highly related genes Cyclin L1 and Cyclin L2 (CCNL1 and CCNL2, respectively). Cyclin L has been shown to associate with the PITSLRE kinase and is involved in pre-mRNA processing. Both Cyclin L gene products can be alternatively spliced to produce two isoforms (known as 1 and 2 or alpha and beta). Cyclin L2 is ubiquitous, expressed at much higher levels than Cyclin L1, and thus is likely the major partner for the CDK11p110 protein kinase.
Gene Name: | cyclin L1 |
Synonyms: | CCNL1, ANIA6A, Ania-6a, BM-001, Cyclin L ania-6a, Cyclin L gamma, Cyclin L1, Cyclin-L, Cyclin-L1, PRO1073 |
Target Sequences: | NM_020307 NP_064703.1 Q9UK58 |
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