CCND3 / Cyclin D3

cyclin D3

Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

☰ Filters

Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

CCND3 / Cyclin D3 (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (2)

GST, N-terminus + His, C-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (6)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Select

Human CCND3 / Cyclin D3 Protein (Recombinant His, N-Terminal) (aa1-292) - LS-G12424

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

36.3 kDa

Price:

50 µg/$432; 10 µg/$279; 200 µg/$862; 100 µg/$690; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

Select

Human CCND3 / Cyclin D3 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G58017

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

CCND3 / Cyclin D3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99549

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.3 kDa

Price:

100 µg/$494

Select

Human CCND3 / Cyclin D3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76012

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.3 kDa

Price:

20 µg/$150

Select

Human CCND3 / Cyclin D3 Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G145249

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

60.3 kDa

Price:

50 µg/$419

Select

Human CCND3 / Cyclin D3 Protein (Recombinant GST) (Full Length) - LS-G27776

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

58.9 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human CCND3 / Cyclin D3 Protein (Recombinant GST, N-terminus) (aa1-292) - LS-G56143

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

Viewing 1-7 of 7 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.