CCND3 / Cyclin D3

cyclin D3

Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

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Products

ELISA Kits (13)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (3)

Development Kit (1)

Sandwich (6)

Sandwich CLIA (1)

Target

CCND3 / Cyclin D3 (13)

Reactivity

Human (5)

Mouse (4)

Rat (6)

Monkey (1)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (3)

96-Well Strip Plate (8)

Antibody Pair and Standard (1)

Publications

No (13)

Sample Type

Adherent Cell Cultures (2)

Cell Culture Supernatants (3)

Cell Lysates (2)

Plasma (5)

Serum (5)

Tissue Homogenates (4)

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Human CCND3 / Cyclin D3 (Sandwich ELISA) ELISA Kit - LS-F14862

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Mouse/Human/Rat CCND3 / Cyclin D3 (Cell-Based ELISA) ELISA Kit - LS-F1927

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Mouse/Human/Rat Phospho-CCND3 / Cyclin D3 (Thr283) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1125

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse CCND3 / Cyclin D3 (Custom ELISA) ELISA Kit - LS-F14861

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Bovine CCND3 / Cyclin D3 (Custom ELISA) ELISA Kit - LS-F14863

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat CCND3 / Cyclin D3 (Custom ELISA) ELISA Kit - LS-F14864

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat CCND3 / Cyclin D3 (CLIA) ELISA Kit - LS-F37516

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

12.5 - 800 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human CCND3 / Cyclin D3 (Sandwich ELISA) ELISA Kit - LS-F38967

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

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Mouse CCND3 / Cyclin D3 (Sandwich ELISA) ELISA Kit - LS-F38299

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Rat CCND3 / Cyclin D3 (Sandwich ELISA) ELISA Kit - LS-F34660

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Monkey CCND3 / Cyclin D3 (Sandwich ELISA) ELISA Kit - LS-F43011

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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DevKit DuoPlus Human CCND3 / Cyclin D3 ELISA Development Kit - LS-F72050

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,276; 1000 Wells/$1,903

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Rat CCND3 / Cyclin D3 (Sandwich ELISA) ELISA Kit - LS-F23569

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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