CCND1 / Cyclin D1

cyclin D1

Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner.

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Products

ELISA Kits (30)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Competitive EIA (2)

Custom (3)

Development Kit (2)

Sandwich (18)

Sandwich CLIA (3)

Target

CCND1 / Cyclin D1 (30)

Reactivity

Human (9)

Mouse (9)

Rat (7)

Chicken (2)

Dog (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Product Group

DevKit DuoPlus (2)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (5)

96-Well Strip Plate (21)

Antibody Pair and Standard (2)

Publications

No (28)

Yes (2)

Sample Type

Adherent Cell Cultures (2)

Cell Culture Supernatants (4)

Cell Lysates (5)

Plasma (14)

Serum (14)

Tissue Homogenates (8)

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Mouse CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F11067

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F35543

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F4095

(4.1) Rating

(2) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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Human CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F22150

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Rat CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F35542

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse/Human/Rat Phospho-CCND1 / Cyclin D1 (Thr286) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1124

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat CCND1 / Cyclin D1 (Cell-Based ELISA) ELISA Kit - LS-F1925

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Bovine CCND1 / Cyclin D1 (Custom ELISA) ELISA Kit - LS-F14853

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Dog CCND1 / Cyclin D1 (Custom ELISA) ELISA Kit - LS-F14854

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Chicken CCND1 / Cyclin D1 (Custom ELISA) ELISA Kit - LS-F14852

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F13111

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Rat CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F11068

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Rat CCND1 / Cyclin D1 (CLIA) ELISA Kit - LS-F37513

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F35541

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CCND1 / Cyclin D1 (CLIA) ELISA Kit - LS-F30221

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse CCND1 / Cyclin D1 (CLIA) ELISA Kit - LS-F30623

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Chicken CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F42997

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Guinea pig CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F42999

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F43000

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Porcine CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F43001

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Sheep CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F43002

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

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Rabbit CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F43004

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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DevKit DuoPlus Mouse CCND1 / Cyclin D1 ELISA Development Kit - LS-F71682

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,207; 1000 Wells/$1,787

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DevKit DuoPlus Human CCND1 / Cyclin D1 ELISA Development Kit - LS-F71579

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,182; 1000 Wells/$1,747

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Rat CCND1 / Cyclin D1 (Sandwich ELISA) ELISA Kit - LS-F55281

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$750

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