CCN5

WNT1 inducible signaling pathway protein 2

WISP2 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. The encoded protein lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.

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Products

Proteins (11)

Type

Over-Expression Lysate (2)

Recombinant (9)

Target

CCN5 (11)

Publications

No (11)

Tag

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (2)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (2)

Rat (1)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (2)

Biologically Active

Biologically active (1)

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Mouse CCN5 Protein (Recombinant 6His-SUMO, N-terminus) (aa24-251) - LS-G22023

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Molecular Weight:

40.5 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Rat CCN5 Protein (Recombinant His) (aa15-250) - LS-G15787

Source:

E. coli

Tag:

His

Molecular Weight:

27.0 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Mouse CCN5 Protein (Recombinant 6His, N-terminus) (aa24-251) - LS-G57375

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human CCN5 Protein (Recombinant) - LS-G131391

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~24.5 kDa

Price:

20 µg/$377

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Human CCN5 Protein (Recombinant) - LS-G84

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

24.3 kDa

Price:

5 µg/$268; 20 µg/$349

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Human CCN5 Protein (Recombinant His) (aa24-250) - LS-G15785

Source:

E. coli

Tag:

His

Molecular Weight:

24.3 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human CCN5 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70899

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.2 kDa

Price:

20 µg/$1,107

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Human CCN5 Protein (Recombinant GST, N-terminus) (aa1-250) - LS-G56621

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human CCN5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88261

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.83 kDa

Price:

20 µg/$150

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Human CCN5 Protein (Recombinant GST) (Full Length) - LS-G31357

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.71 kDa

Price:

10 µg/$479; 25 µg/$670

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CCN5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100162

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.83 kDa

Price:

100 µg/$494

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