CCN4 / WISP1

WNT1 inducible signaling pathway protein 1

CCN4 / WISP1 is a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified.

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Products

ELISA Kits (19)

Type

Custom (1)

Sandwich (16)

Sandwich CLIA (2)

Target

CCN4 / WISP1 (19)

Reactivity

Human (9)

Mouse (6)

Rat (4)

Format

96-Well Microplate (3)

96-Well Strip Plate (15)

Publications

No (19)

Sample Type

Cell Culture Supernatants (7)

Cell Lysates (1)

EDTA Plasma (1)

Heparin Plasma (1)

Plasma (17)

Serum (18)

Tissue Homogenates (9)

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Human CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F38167

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Rat CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F55355

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Rat CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F57259

Type:

Sandwich

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Sample Types:

Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$699

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Mouse CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F12967

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

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Human CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F12968

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat CCN4 / WISP1 (Custom ELISA) ELISA Kit - LS-F16067

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$585

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Human CCN4 / WISP1 (CLIA) ELISA Kit - LS-F26572

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.14 - 100 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$851

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Mouse CCN4 / WISP1 (CLIA) ELISA Kit - LS-F26573

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

2.74 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$871

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Rat CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F34083

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F37305

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F37306

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F52818

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$822

Select

Mouse CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F24913

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$624

Select

Human CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F24706

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$624

Select

Human CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F214

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

61.44 - 6000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

Select

Human CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F2884

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$901

Select

Mouse CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F2877

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$901

Select

Human CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F7053

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$730

Select

Mouse CCN4 / WISP1 (Sandwich ELISA) ELISA Kit - LS-F7184

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$549

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