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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600
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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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CCL3 / MIP-1-Alpha
chemokine (C-C motif) ligand 3
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
| Gene Name: | chemokine (C-C motif) ligand 3 |
| Family/Subfamily: | Intercrine , Intercrine beta |
| Synonyms: | CCL3, C-C motif chemokine 3, G0S19-1, Mip1alpha, SCYA3, SIS-beta, Chemokine (C-C motif) ligand 3, LD78ALPHA, MIP-1-alpha, MIP1A, PAT 464.1, Small-inducible cytokine A3 |
| Target Sequences: | NM_002983 NP_002974.1 |
Publications (2)
1
Chemokine (C-C motif) ligand 3 detection in the serum of persons exposed to asbestos: A patient-based study. Xu J, Alexander DB, Iigo M, Hamano H, Takahashi S, Yokoyama T, Kato M, Usami I, Tokuyama T, Tsutsumi M, Tamura M, Oguri T, Niimi A, Hayashi Y, Yokoyama Y, Tonegawa K, Fukamachi K, Futakuchi M, Sakai Y, Suzui M, Kamijima M, Hisanaga N, Omori T, Nakae D, Hirose A, Kanno J, Tsuda H. Cancer science. 2015 106:825-32. (IHC-P; Human)
[Full Text Article]
[PubMed:25940505]
[PMC:PMC4520633]
2
CCL3-CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways. Takayuki Kodama, Yu-Ichiro Koma, Noriaki Arai, Aya Kido, Naoki Urakawa, Mari Nishio, Manabu Shigeoka, Hiroshi Yokozaki. Laboratory investigation; a journal of technical methods and pathology. 2020 September;100:1140-1157. [Full Text Article]
[PubMed:32457351]
[PMC:PMC7438203]
Related Antibodies: LS-C384561.
☰ Filters
Products
Proteins
(40)
Type
Over-Expression Lysate
(2)
Recombinant
(35)
Target
CCL3 / MIP-1-Alpha
(40)
Application
SDS-PAGE
(2)
Product Group
Coronavirus Antibodies Proteins cDNAs
(40)
Cytokine Release Syndrome
(40)
Cytokine Release Syndrome Proteins
(40)
Format
Animal-free
(1)
Publications
No
(40)
Tag
6His, N-terminus
(1)
7His, C-terminus
(1)
GST
(1)
GST, N-terminus
(1)
His
(5)
His, N-Terminal
(4)
His,C-terminus
(1)
His-GST
(4)
Myc-DDK (Flag)
(3)
Species
Bovine
(1)
Dog
(1)
Human
(23)
Mouse
(11)
Rat
(3)
Source
293F Cells
(2)
293T Cells
(1)
E. coli
(26)
Eukaryotic cells
(1)
HEK 293 Cells
(4)
Wheat Germ Extract
(2)
Yeast
(3)
Purification
Purified
(16)
Low Endotoxin Level
Low endotoxin level
(16)
Biologically Active
Biologically active
(10)
Animal-free
Animal-free
(1)
HEK 293 Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
7.8 kDa (SDS-PAGE)
5 µg/$268; 25 µg/$308
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
7.8 kDa
5 µg/$268; 20 µg/$349
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5 µg/$282; 20 µg/$370
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
7.8 kDa
2 µg/$268; 10 µg/$349
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
7.8 kDa
5 µg/$268; 20 µg/$349
E. coli
None
Biologically active
7.8 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
7.9 kDa
100 µg/$957; 500 µg/$1,747; 10 µg/$388
E. coli
None
Biologically active
7.9 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
7.5kD
10 µg/$297; 50 µg/$468; 500 µg/$1,585; 1 mg/$2,157
E. coli
7His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
10.8kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Wheat Germ Extract
GST
36.5 kDa
10 µg/$479; 25 µg/$670
E. coli
None
SDS-PAGE
The recombinant mouse CCL3consists of 70 amino acids and predicts a molecular mass of 8.01 kDa. It migrates as an approximately 8-14 kDa band in SDS-PAGE under reducing conditions.
20 µg/$333; 100 µg/$519
Yeast
His,C-terminus
SDS-PAGE
The recombinant human CCL3 consists of 80 amino acids and predicts a molecular mass of 9.2 kDa. It migrates as an approximately 14 kDa band in SDS-PAGE under reducing conditions.
50 µg/$403; 1 mg/$2,675
293T Cells
Myc-DDK (Flag)
9.9 kDa
20 µg/$150
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
9.9 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
9.9 kDa
100 µg/$494
HEK 293 Cells
His, N-Terminal
8.8 kDa
50 µg/$1,111
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$291; 100 µg/$490; 1 mg/$1,813
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
7.5 kDa
50 µg/$556; 10 µg/$324; 1 mg/$2,837; 500 µg/$1,987
E. coli
None
7.8 kDa
5 µg/$329; 20 µg/$412; 1000 µg/$3,417
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
7.5 kDa
20 µg/$360; 100 µg/$728
E. coli
68 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
7.59 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
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product results
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