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CCL27

chemokine (C-C motif) ligand 27

CCL27 is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.

Gene Name: chemokine (C-C motif) ligand 27
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL27, ALP, Chemokine alp, C-C motif chemokine 27, CC chemokine ILC, CTAK, ESKINE, IL-11 R-alpha-locus chemokine, ILC, IL-11 Ralpha-locus chemokine, PESKY, SCYA27, Skinkine, CTACK, Il-11r alpha-locus chemokine, Small-inducible cytokine A27
Target Sequences: NM_006664 NP_006655.1 Q9Y4X3

☰ Filters
Products
Proteins (15)
Over-Expression Lysate (2)
Recombinant (12)
CCL27 (15)
No (15)
6His, N-terminus (1)
GST (1)
His-S (1)
Myc-DDK (Flag) (2)
Human (12)
Mouse (2)
293T Cells (1)
E. coli (12)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (7)
Low endotoxin level (7)
Biologically active (6)
CCL27 Protein
Select
E. coli
None
100 µg/$342; 500 µg/$641; 20 µg/$254
CCL27 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
12.62 kDa
100 µg/$494
Select
E. coli
None
Less than 0.01 EU/µg protein (determined by LAL method).
10.1 kDa
5 µg/$279; 20 µg/$354; 50 µg/$456; 100 µg/$634; 1000 µg/$2,337
CCL27 Protein - Baf3-hCCR10 transfectants chemoattracted by human CCL27.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 88 amino acid recombinant protein has a predicted molecular mass of approximately 10 kD. The DTT-reduced protein migrates at approximately 11 kD and non-reduced protein migrates at 12 kD by SDS-PAGE. The N-terminal amino acid is Phe.
10 µg/$306; 100 µg/$731
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~10.4 kDa
20 µg/$395; 1 mg/$4,915
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
10.1 kDa
10 µg/$297; 50 µg/$460
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
10.9 kDa
5 µg/$268; 20 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
10.2 kDa
5 µg/$268; 20 µg/$349
CCL27 Protein
Select
E. coli
None
Biologically active
10.9 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
CCL27 Protein
Select
E. coli
None
Biologically active
10.1 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
CCL27 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
12.62 kDa
20 µg/$150
Select
E. coli
His-S
15.8 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
CCL27 Protein
Select
E. coli
6His, N-terminus
12.5 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 250 µg/$518
CCL27 Protein - 12.5% SDS-PAGE of human CCL27 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
37.95 kDa
2 µg/$439
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
10.1kD
10 µg/$297; 50 µg/$468; 500 µg/$1,353; 1 mg/$1,725
Viewing 1-15 of 15 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).