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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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CCL17 / TARC
chemokine (C-C motif) ligand 17
This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.
| Gene Name: | chemokine (C-C motif) ligand 17 |
| Family/Subfamily: | Intercrine , Intercrine beta |
| Synonyms: | CCL17, A-152E5.3, C-C motif chemokine 17, CC chemokine abcd-2, ABCD-2, SCYA17, T cell-directed CC chemokine, TARC, CC chemokine TARC, Small-inducible cytokine A17 |
| Target Sequences: | NM_002987 NP_002978.1 Q92583 |
Publications (1)
1
Cancer associated fibroblasts (CAFs) are activated in cutaneous basal cell carcinoma and in the peritumoural skin. Omland SH, Wettergren EE, Mollerup S, Asplund M, Mourier T, Hansen AJ, Gniadecki R. BMC cancer. 2017 17:675. (IHC, ELISA; Human)
[Full Text Article]
[PubMed:28987144]
[PMC:PMC5806272]
Related Antibodies: LS-C198166.
☰ Filters
Products
Proteins
(18)
Type
Over-Expression Lysate
(2)
Recombinant
(16)
Target
CCL17 / TARC
(18)
Publications
No
(18)
Tag
GST, N-terminus
(1)
His
(5)
His, C-Terminal
(1)
His,C-terminus
(1)
Myc-DDK (Flag)
(2)
Species
Human
(12)
Mouse
(3)
Rat
(2)
Source
293T Cells
(1)
E. coli
(13)
HEK 293 Cells
(1)
Human
(1)
Mammalian Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(7)
Low Endotoxin Level
Low endotoxin level
(8)
Biologically Active
Biologically active
(8)
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.0 kDa
5 µg/$268; 20 µg/$349
E. coli
His
9.6 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
E. coli
None
Biologically active
8.1 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
7.9 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
E. coli
None
Biologically active
8.1 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
E. coli
His
9.3 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
E. coli
His
9.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His
9.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
293T Cells
Myc-DDK (Flag)
10.51 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
10.51 kDa
100 µg/$494
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 71 amino acid recombinant protein has a predicted molecular mass of approximately 7.98 kD. The DTT-reduced protein migrates at approximately 12 kD and non-reduced protein at approximately 14 kD by SDS-PAGE. The N-terminal amino acid is Ala.
10 µg/$291; 25 µg/$375; 100 µg/$782
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 71 amino acid recombinant protein has a predicted molecular mass of approximately 8 kD. The DTT-reduced protein migrates at approximately 10 kD and non-reduced protein migrates at approximately 11 kD by SDS-PAGE. The N-terminal amino acid is Ala.
10 µg/$283; 25 µg/$359; 100 µg/$744
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
8.1 kDa
1 mg/$2,880; 20 µg/$372
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
9.1 kDa
10 µg/$266; 50 µg/$371
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
50 µg/$361; 250 µg/$739; 10 µg/$261
Human
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
9.1kD
10 µg/$266; 50 µg/$376; 500 µg/$1,067; 1 mg/$1,369
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$381; 1 mg/$3,781
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