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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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CCL11 / Eotaxin

chemokine (C-C motif) ligand 11

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Gene Name: chemokine (C-C motif) ligand 11
Family/Subfamily: Intercrine , Intercrine beta
Synonyms: CCL11, C-C motif chemokine 11, Eotaxin-1, SCYA11, Small-inducible cytokine A11, Eosinophil chemotactic protein, Eotaxin
Target Sequences: NM_002986 NP_002977.1 P51671

Publications (2)

1
Eosinophils in Colorectal Neoplasms Associated with Expression of CCL11 and CCL24. Cho H, Lim SJ, Won KY, Bae GE, Kim GY, Min JW, Noh BJ. Journal of pathology and translational medicine. 2016 50:45-51. (IHC, WB; Human) [Full Text Article] [PubMed:26657310] [PMC:PMC4734969]
2
Peripheral Nerve Single-Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth. Jeremy S Toma, Konstantina Karamboulas, Matthew J Carr, Adelaida Kolaj, Scott A Yuzwa, Neemat Mahmud, Mekayla A Storer, David R Kaplan, Freda D Miller. eNeuro. 2020 May;7: [Full Text Article] [PubMed:32349983] [PMC:PMC7294463]

☰ Filters
Products
Proteins (26)
Over-Expression Lysate (2)
Recombinant (24)
CCL11 / Eotaxin (26)
No (26)
GST (1)
GST, N-terminus (1)
His (2)
His-GST (3)
His-GST, N-terminus (1)
Myc-DDK (Flag) (2)
Bovine (1)
Horse (1)
Human (13)
Mouse (6)
Rat (3)
Rhesus monkey (1)
293T Cells (1)
E. coli (23)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (13)
Low endotoxin level (13)
Biologically active (12)
Animal-free (1)
CCL11 / Eotaxin Protein - Baf3-hCCR3 transfectants chemoattracted by human CCL11.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 74 amino acid recombinant protein has a predicted molecular mass of approximately 8.4 kD. The DTT-reduced protein migrates at approximately 12 kD and non-reduced protein migrates at approximately 14 kD by SDS-PAGE. The N-terminal amino acid is Glycine
10 µg/$294; 25 µg/$359; 100 µg/$731
CCL11 / Eotaxin Protein
Select
E. coli
None
Biologically active
8.4 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
CCL11 / Eotaxin Protein
Select
E. coli
None
Biologically active
8.4 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
CCL11 / Eotaxin Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$291; 100 µg/$517; 1 mg/$2,851
Select
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.4 kDa
5 µg/$268; 20 µg/$349
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.3 kDa
5 µg/$268; 20 µg/$349
CCL11 / Eotaxin Protein
Select
E. coli
None
Biologically active
8.4 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
CCL11 / Eotaxin Protein
Select
E. coli
None
Biologically active
8.4 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
CCL11 / Eotaxin Protein - Recombinant Eosinophil Chemotactic Factor By SDS-PAGE
Select
E. coli
His-GST
40.8 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
CCL11 / Eotaxin Protein - Recombinant Eosinophil Chemotactic Factor By SDS-PAGE
Select
E. coli
His-GST
40.8 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
8.56kD
10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157
CCL11 / Eotaxin Protein - 12.5% SDS-PAGE of human CCL11 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
33.88 kDa
10 µg/$479; 25 µg/$670
CCL11 / Eotaxin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
10.73 kDa
100 µg/$494
CCL11 / Eotaxin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
10.73 kDa
20 µg/$150
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
8.4 kDa
1 mg/$2,880; 20 µg/$372
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
8.4 kDa
1 mg/$2,885; 20 µg/$376
Select
E. coli
None
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
8.3 kDa
20 µg/$370; 5 µg/$282
CCL11 / Eotaxin Protein - Baf3-hCCR3 transfectants chemoattracted by mouse CCL11.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 74 amino acid recombinant protein has a predicted molecular mass of approximately 8.4 kD. The DTT-reduced protein migrates at approximately 12 kD and non-reduced protein migrates at approximately 14 kD by SDS-PAGE. The N-terminal amino acid is Histidi
10 µg/$294; 25 µg/$359; 100 µg/$731
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
8.6 kDa
10 µg/$281; 50 µg/$414
CCL11 / Eotaxin Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~9 kDa
20 µg/$291; 1 mg/$2,551
CCL11 / Eotaxin Protein - Recombinant Eosinophil Chemotactic Factor (ECF) by SDS-PAGE
Select
E. coli
His-GST, N-terminus
38kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
CCL11 / Eotaxin Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$291; 100 µg/$494; 1 mg/$2,851
CCL11 / Eotaxin Protein - Recombinant Eosinophil Chemotactic Factor By SDS-PAGE
Select
E. coli
His
12.3 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
CCL11 / Eotaxin Protein - Recombinant Eosinophil Chemotactic Factor By SDS-PAGE
Select
E. coli
His-GST
38.9 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
CCL11 / Eotaxin Protein
Select
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$342; 500 µg/$641; 20 µg/$254
Viewing 1-25 of 26 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).