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CCKBR / Cckb
cholecystokinin B receptor
Receptor for gastrin and cholecystokinin. The CKK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.Isoform 2 is constitutively activated and may regulate cancer cell proliferation via a gastrin-independent mechanism.
| Gene Name: | cholecystokinin B receptor |
| Family/Subfamily: | GPCR , Cholecystokinin |
| Synonyms: | CCKBR, CCKB, Cholecystokinin-2 receptor, CCK-BR, CCK2 receptor, CCK2-R, CCKB-R, Cholecystokinin-B, GASR, CCK-B, CCK-B receptor, CCK2R, Cckb receptor, CCKRB, Cholecystokinin B receptor, Gastrin receptor |
| Target Sequences: | NM_176875 NP_795344.1 P32239 |
Publications (4)
1
Control of somatostatin (SS) secretion by CCK-1 and CCK-2 receptors' occupation in RIN-14B cells, a rat pancreatic islet cell line. El-Kouhen K, Morisset J. Pancreas. 2010 39:127-34. (IF; Rat)
[PubMed:19959964]
Related Antibodies: LS-B2325.
2
Cholecystokinin and Somatostatin Negatively Affect Growth of the Somatostatin-RIN-14B Cells. El-Kouhen K, Morisset J. International journal of endocrinology. 2009 2009:875167.
[PubMed:20011057]
[PMC:PMC2778184]
Related Antibodies: LS-B2325.
3
CCK1 and CCK2 receptors are expressed on pancreatic stellate cells and induce collagen production. Berna MJ, Seiz O, Nast JF, Benten D, Blker M, Koch J, Lohse AW, Pace A. The Journal of biological chemistry. 2010 285:38905-14.
[PubMed:20843811]
[PMC:PMC2998120]
Related Antibodies: LS-B2325.
☰ Filters
Products
ELISA Kits
(13)
Type
Custom
(5)
Sandwich
(8)
Target
CCKBR / Cckb
(13)
Reactivity
Human
(3)
Mouse
(2)
Rat
(1)
Chicken
(1)
Dog
(1)
Guinea pig
(1)
Monkey
(1)
Rabbit
(1)
Sheep
(1)
Format
96-Well Strip Plate
(13)
Publications
No
(13)
Sample Type
Plasma
(2)
Serum
(2)
Tissue Homogenates
(1)
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Guinea pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Rabbit
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$798
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
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