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CCKAR / CCK1R

cholecystokinin A receptor

Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Gene Name: cholecystokinin A receptor
Family/Subfamily: GPCR , Cholecystokinin
Synonyms: CCKAR, CCK-A receptor, CCK-AR, CCKRA, CCK-A, CCKA receptor, Cholecystokinin A receptor, Cck1r, CCK1-R, Cholecystokinin-1 receptor
Target Sequences: NM_000730 NP_000721.1 P32238

Publications (2)

1
Control of somatostatin (SS) secretion by CCK-1 and CCK-2 receptors' occupation in RIN-14B cells, a rat pancreatic islet cell line. El-Kouhen K, Morisset J. Pancreas. 2010 39:127-34. (IF; Rat) [PubMed:19959964] Related Antibodies: LS-C54623.
2
Cholecystokinin and Somatostatin Negatively Affect Growth of the Somatostatin-RIN-14B Cells. El-Kouhen K, Morisset J. International journal of endocrinology. 2009 2009:875167. [PubMed:20011057] [PMC:PMC2778184] Related Antibodies: LS-C54623.

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Products
Antibodies (39)
Primary (39)
CCKAR / CCK1R (39)
Human (35)
Mouse (13)
Rat (15)
Bat (1)
Bovine (4)
Chimpanzee (6)
Dog (4)
Gibbon (3)
Horse (6)
Monkey (5)
Rabbit (3)
IHC (8)
IHC-Fr (2)
IHC-P (6)
WB (26)
Flo (1)
ELISA (11)
ICC (1)
IF (4)
IP (1)
Peptide-ELISA (4)
rabbit (36)
mouse (1)
goat (2)
Product Group
GPCR Database Antibodies (4)
IHCPlus (4)
IgG (17)
IgG2a (1)
monoclonal mc (1)
polyclonal pc (38)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
Concentrated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (25)
aa228-257 (7)
aa21-70 (4)
aa242-291 (4)
C-Terminus (3)
Internal (3)
190-270 aa, Internal (1)
N-Terminus (1)
Pro255 (1)
aa170-183 (1)
aa180-195 (1)
aa197-210 (1)
aa215-264 (1)
aa242-257 (1)
aa325-356 (1)
No (38)
Yes (1)
CCKAR / CCK1R Antibody - Anti-CCKAR antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
CCKAR / CCK1R Antibody - Anti-CCKAR / CCK1R antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC-P
Unconjugated
50 µg/$440
CCKAR / CCK1R Antibody - Western blot of CCK-AR (P255) pAb in extracts from HeLa and PC12 cells.
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (Pro255) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µl/$391
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (190-270 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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CCKAR / CCK1R Goat anti-Mouse Polyclonal (aa170-183) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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CCKAR / CCK1R Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
100 µg/$872
CCKAR / CCK1R Antibody - Anti-CCKAR antibody IHC of human gall bladder, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
CCKAR / CCK1R Antibody - Anti-CCKAR antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (Internal) Antibody
Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
CCKAR / CCK1R Antibody - Antibody (10 ug/ml) staining of paraffin embedded Human Pancreas. Microwaved antigen retrieval with citrate buffer pH 6, HRP-staining.
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CCKAR / CCK1R Goat anti-Human Polyclonal (aa242-257) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
100 µg/$503
CCKAR / CCK1R Antibody - Western blot analysis of lysates from HepG2 and Jurkat cells, using CCKAR Antibody. The lane on the right is blocked with the synthesized peptide.
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (aa215-264) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CCKAR / CCK1R Antibody - Immunohistochemistry image at a dilution of 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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CCKAR / CCK1R Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
CCKAR / CCK1R Antibody - Immunofluorescent analysis of CCKAR staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (Internal) Antibody
Rat, Human
ICC, IF, IP, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (aa197-210) Antibody
Human
ELISA, WB
Unconjugated
20 µl/$483; 100 µl/$832
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (aa228-257) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (aa228-257) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (aa228-257) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (aa228-257) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (aa228-257) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (aa228-257) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
CCKAR / CCK1R Antibody - Western blot analysis of extracts from HUVEC cells, using CCKAR antibody.
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CCKAR / CCK1R Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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CCKAR / CCK1R Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Mouse, Rat
IHC, IHC-Fr
Unconjugated
50 µl/$1,166
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CCKAR / CCK1R Rabbit anti-Rat Polyclonal (C-Terminus) (Concentrated) Antibody
Rat
IHC, IHC-Fr
Unconjugated, Concentrated
50 µl/$894
CCKAR / CCK1R Antibody - Western blot analysis of extracts of HuvEc cells using CCKAR antibody.
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CCKAR / CCK1R Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCKAR / CCK1R Antibody - Mouse Cckar Antibody western blot of mouse bladder, cerebellum and lung tissue lysates (35 ug/lane). The Mouse Cckar antibody detected the Mouse Cckar protein (arrow).
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CCKAR / CCK1R Rabbit anti-Mouse Polyclonal (aa325-356) Antibody
Mouse
WB
Unconjugated
400 µl/$393
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CCKAR / CCK1R Rabbit anti-Human Polyclonal (aa180-195) Antibody
Mouse, Bovine, Rat, Bat, Human
ELISA
Unconjugated
20 µl/$483; 100 µl/$832
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).