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CCK4 / PTK7

protein tyrosine kinase 7

PTK7, a CCK4 membrane spanning tyrosine protein kinase, belongs to a subgroup of kinases that lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. PTK7 may function as a cell adhesion molecule. This gene was isolated from carcinomic colon tissue and has been suggested to affect colon carcinoma physiology. Expression of PTK7 has been shown to be reduced in melanoma samples. Five transcript variants encoding five different isoforms have been found for this gene.

Gene Name: protein tyrosine kinase 7
Family/Subfamily: Protein Kinase , CCK4
Synonyms: PTK7, CCK-4, CCK4, Colon carcinoma kinase 4, Tyrosine-protein kinase-like 7, Protein-tyrosine kinase 7, PTK7 protein tyrosine kinase 7
Target Sequences: NM_002821 NP_002812.2 Q13308

Publications (1)

1
ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease. Hayes M, Gao X, Yu LX, Paria N, Henkelman RM, Wise CA, Ciruna B. Nature communications. 2014 5:4777. (WB; Human) [Full Text Article] [PubMed:25182715] [PMC:PMC4155517] Related Antibodies: LS-C79252.

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Products
Antibodies (51)
Primary (51)
CCK4 / PTK7 (51)
Human (51)
Mouse (13)
Rat (8)
Chicken (1)
IHC (23)
IHC-P (5)
WB (37)
Flo (5)
ELISA (20)
IF (9)
IP (2)
Peptide-ELISA (2)
rabbit (37)
mouse (13)
goat (1)
Product Group
IHCPlus (2)
IgG (24)
IgG1 (7)
IgG2a (2)
IgG2b,k (4)
monoclonal mc (13)
polyclonal pc (38)
11C630 (1)
4C6 (1)
4F9 (2)
OTI1G4 (2)
OTI2E7 (2)
OTI2H4 (2)
APC (1)
APC Conjugated (4)
Azide-free (3)
Biotin Conjugated (5)
Carrier-free (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (4)
Unconjugated (28)
N-Terminus (8)
aa21-52 (7)
aa36-146 (3)
aa31-199 (2)
aa331-363 (1)
aa700-750 (1)
aa722-757 (1)
aa750-800 (1)
No (50)
Yes (1)
CCK4 / PTK7 Antibody - Anti-CCK4 / PTK7 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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CCK4 / PTK7 Mouse anti-Human Monoclonal (aa31-199) (4F9) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$440
CCK4 / PTK7 Antibody - Anti-PTK7 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CCK4 / PTK7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
CCK4 / PTK7 Antibody - Anti-PTK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTK7.
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CCK4 / PTK7 Mouse anti-Human Monoclonal (OTI2E7) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
CCK4 / PTK7 Antibody - Anti-PTK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTK7.
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CCK4 / PTK7 Mouse anti-Human Monoclonal (Carrier-free) (OTI2E7) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
CCK4 / PTK7 Antibody - Immunohistochemistry of PTK7 in human colon tissue with PTK7 antibody at 5 ug/ml.
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CCK4 / PTK7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
CCK4 / PTK7 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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CCK4 / PTK7 Rabbit anti-Human Polyclonal (aa21-52) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
CCK4 / PTK7 Antibody - Anti-PTK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTK7.
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CCK4 / PTK7 Mouse anti-Human Monoclonal (OTI2H4) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
CCK4 / PTK7 Antibody - Anti-PTK7 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTK7.
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CCK4 / PTK7 Mouse anti-Human Monoclonal (Carrier-free) (OTI2H4) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
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CCK4 / PTK7 Goat anti-Human Polyclonal (aa31-199) Antibody
Human
WB
Unconjugated
100 µg/$930
CCK4 / PTK7 Antibody - Immunofluorescence of monoclonal antibody to PTK7 on HeLa cell. [antibody concentration 10 ug/ml]
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CCK4 / PTK7 Mouse anti-Human Monoclonal (4C6) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
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CCK4 / PTK7 Mouse anti-Human Monoclonal (aa36-146) (Biotin) (11C630) Antibody
Human
ELISA, IF, WB
Biotin Conjugated
100 µl/$904
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CCK4 / PTK7 Mouse anti-Human Monoclonal (aa36-146) (APC) Antibody
Human
ELISA, IF, WB
APC Conjugated
100 µl/$904
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CCK4 / PTK7 Mouse anti-Human Monoclonal (aa36-146) (Azide-free) Antibody
Human
IF, WB
Unconjugated, Azide-free
100 µg/$705
CCK4 / PTK7 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTK7 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTK7.
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CCK4 / PTK7 Mouse anti-Human Monoclonal (OTI1G4) Antibody
Human
WB
Unconjugated
100 µl/$434
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CCK4 / PTK7 Rabbit anti-Human Polyclonal (APC) Antibody
Human
APC Conjugated
100 µl/$387; 200 µl/$462; 500 µl/$774; 1 ml/$929; 2 ml/$1,189; 5 ml/$2,199
CCK4 / PTK7 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded Lung Cancer Tissues with DAB staining using CCK-4 Monoclonal Antibody.
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CCK4 / PTK7 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
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CCK4 / PTK7 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
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CCK4 / PTK7 Rabbit anti-Human Polyclonal (aa21-52) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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CCK4 / PTK7 Rabbit anti-Human Polyclonal (aa21-52) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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CCK4 / PTK7 Rabbit anti-Human Polyclonal (aa21-52) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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CCK4 / PTK7 Rabbit anti-Human Polyclonal (aa21-52) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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CCK4 / PTK7 Rabbit anti-Human Polyclonal (aa21-52) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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CCK4 / PTK7 Rabbit anti-Human Polyclonal (aa21-52) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
CCK4 / PTK7 Antibody - Immunohistochemistry of paraffin-embedded mouse brain tissue.
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CCK4 / PTK7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CCK4 / PTK7 Antibody
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CCK4 / PTK7 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).