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CCBL1

cysteine conjugate-beta lyase, cytoplasmic

Kidney cysteine conjugate beta-lyase (kyneurenine aminotranferase 1) metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites that can produce nephrotoxicity and neurotoxicity. KAT1 also catalyses the reversible transamination of glutamine to oxoglutaramic acid and converts kynurenine into kynurenic acid (KYNA), a broadspectrum antagonist at ionotropic excitatory amino acid receptors. It exists in a cytosolic and a mitochondrial form due to the presence of KAT1 mRNAs coding for proteins with and without leader sequences.

Gene Name: cysteine conjugate-beta lyase, cytoplasmic
Synonyms: CCBL1, Beta-lysase, kidney, KAT1, KATI, Kynurenine aminotransferase I, Kyneurenine aminotransferase, Kynurenic acid transferase 1, GTK, Glutamine transaminase K
Target Sequences: NM_004059 NP_004050.3 Q16773

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Products
Antibodies (27)
Primary (27)
CCBL1 (27)
Human (27)
Mouse (3)
Rat (3)
Hamster (1)
Monkey (1)
IHC (9)
IHC-P (6)
WB (22)
ELISA (12)
ICC (1)
IF (4)
Peptide-ELISA (2)
rabbit (24)
mouse (2)
goat (1)
Product Group
IHCPlus (1)
IgG (15)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (26)
1B12 (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (12)
aa1-422 (8)
aa327-355 (7)
aa1-372 (4)
aa343-353 (1)
No (27)
CCBL1 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CCBL1 Mouse anti-Human Monoclonal (1B12) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CCBL1 Antibody - Immunohistochemistry of paraffin-embedded mouse liver tissue.
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CCBL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CCBL1 Antibody - Immunohistochemical analysis of CCBL1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CCBL1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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CCBL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CCBL1 Antibody - Immunohistochemistry of paraffin-embedded human small intestine tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-372) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
CCBL1 Antibody - Immunohistochemistry of paraffin-embedded human small intestine tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-372) (HRP) Antibody
Human
ELISA, IHC, IHC-P
HRP Conjugated
50 µg/$294; 100 µg/$360
CCBL1 Antibody - Immunohistochemistry of paraffin-embedded human small intestine tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-372) (Biotin) Antibody
Human
ELISA, IHC, IHC-P
Biotin Conjugated
50 µg/$294; 100 µg/$360
CCBL1 Antibody - Immunohistochemistry of paraffin-embedded human small intestine tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-372) (FITC) Antibody
Human
ELISA, IHC, IHC-P
FITC Conjugated
50 µg/$294; 100 µg/$360
CCBL1 Antibody - 1:100 staining human lymph carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CCBL1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CCBL1 Rabbit anti-Human Polyclonal (aa327-355) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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CCBL1 Rabbit anti-Human Polyclonal (aa327-355) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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CCBL1 Rabbit anti-Human Polyclonal (aa327-355) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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CCBL1 Rabbit anti-Human Polyclonal (aa327-355) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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CCBL1 Rabbit anti-Human Polyclonal (aa327-355) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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CCBL1 Rabbit anti-Human Polyclonal (aa327-355) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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CCBL1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
CCBL1 Antibody - CCBL1 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The CCBL1 antibody detected the CCBL1 protein (arrow).
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CCBL1 Rabbit anti-Human Polyclonal (aa327-355) Antibody
Human
WB
Unconjugated
400 µl/$393
CCBL1 Antibody - Western blot of CCBL1 antibody.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-422) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
CCBL1 Antibody - Western blot of CCBL1 antibody.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-422) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
CCBL1 Antibody - Western blot of CCBL1 antibody.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-422) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
CCBL1 Antibody - Western blot of CCBL1 antibody.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-422) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
CCBL1 Antibody - Western blot of CCBL1 antibody.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-422) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
CCBL1 Antibody - Western blot of CCBL1 antibody.
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CCBL1 Rabbit anti-Human Polyclonal (aa1-422) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
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CCBL1 Goat anti-Human Polyclonal (aa343-353) Antibody
Hamster, Human, Monkey
Peptide-ELISA
Unconjugated
100 µg/$401
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CCBL1 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 27 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).