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Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Gene Name: | chromobox homolog 6 |
Synonyms: | CBX6, Chromobox homolog 6, Chromobox protein homolog 6 |
Target Sequences: | NM_014292 NP_055107.3 O95503 |
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