CASR/Calcium Sensing Receptor

calcium-sensing receptor

CASR, a Calcium-Sensing Receptor, functions as a sensor in parathyroid and kidney to determine extracellular calcium concentration and to maintain calcium homeostasis. This receptor regulates both secretion of parathyroid hormone and excretion of urinary calcium. Mutations that inactivate CASR cause familial hypocalciuric hypercalcemia, which is also correlated with hyperparathyroidism. On the other hand, mutations that activate CASR cause autosomal dominant hypocalcemia. Hjalm et al. (2001) and Awata et al. (2001) have identified the binding of filamin-1 to the C-terminal tail of CASR, which may contribute to its localization in caveolae, link it to the actin-based cytoskeleton, and participate in CASR-mediated activation of MAPK. Multiple isoforms for CASR are produced by alternative splicing.

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Products

ELISA Kits (22)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Competitive EIA (1)

Custom (3)

Sandwich (15)

Sandwich CLIA (1)

Target

CASR/Calcium Sensing Receptor (22)

Reactivity

Human (6)

Mouse (6)

Rat (7)

Bovine (1)

Chicken (1)

Guinea pig (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (4)

96-Well Strip Plate (17)

Publications

No (22)

Sample Type

Adherent Cell Cultures (2)

Cell Lysates (3)

Plasma (9)

Serum (9)

Tissue Homogenates (6)

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Human CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F34626

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse/Human/Rat CASR/Calcium Sensing Receptor (Cell-Based ELISA) ELISA Kit - LS-F1840

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Human CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F17840

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Mouse/Human/Rat Phospho-CASR/Calcium Sensing Receptor (Thr888) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1321

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F9431

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$748

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Human CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F37836

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F35526

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F35527

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat CASR/Calcium Sensing Receptor (CLIA) ELISA Kit - LS-F31141

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Chicken CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F41851

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Porcine CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F41853

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Guinea pig CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F41852

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F41854

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Rabbit CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F41855

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Mouse CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F21319

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Rat CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F21502

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Pig CASR/Calcium Sensing Receptor (Custom ELISA) ELISA Kit - LS-F17836

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat CASR/Calcium Sensing Receptor (Custom ELISA) ELISA Kit - LS-F17837

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Bovine CASR/Calcium Sensing Receptor (Competitive EIA) ELISA Kit - LS-F17838

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

0.15 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Mouse CASR/Calcium Sensing Receptor (Custom ELISA) ELISA Kit - LS-F17839

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Human CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F25370

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$730

Select

Rat CASR/Calcium Sensing Receptor (Sandwich ELISA) ELISA Kit - LS-F25371

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$783

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