CASP5 / Caspase 5

caspase 5, apoptosis-related cysteine peptidase

CASP5 / Caspase 5 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

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Products

Proteins (9)

Type

Over-Expression Lysate (4)

Recombinant (5)

Target

CASP5 / Caspase 5 (9)

Publications

No (9)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His, N-Terminal (2)

His-SUMO (1)

Myc-DDK (Flag) (4)

Species

Human (7)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

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Human CASP5 / Caspase 5 Protein (Recombinant His, N-Terminal) - LS-G144031

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

47.7 kDa

Price:

50 µg/$419

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Human CASP5 / Caspase 5 Protein (Recombinant His, N-Terminal) (aa145-327) - LS-G12770

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

24.5 kDa

Price:

10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113

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Human CASP5 / Caspase 5 Protein (Recombinant GST, N-terminus) (aa309-418) - LS-G57990

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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CASP5 / Caspase 5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100270

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.7 kDa

Price:

100 µg/$494

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Human CASP5 / Caspase 5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75029

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.1 kDa

Price:

20 µg/$150

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Human CASP5 / Caspase 5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75030

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.7 kDa

Price:

20 µg/$150

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CASP5 / Caspase 5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125644

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.1 kDa

Price:

100 µg/$494

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Human CASP5 / Caspase 5 Protein (Recombinant His-SUMO) (aa137-327) - LS-G20561

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

37.81 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human CASP5 / Caspase 5 Protein (Recombinant 6His, N-terminus) (aa137-327) - LS-G57132

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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