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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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CASP5 / Caspase 5
caspase 5, apoptosis-related cysteine peptidase
CASP5 / Caspase 5 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.
| Gene Name: | caspase 5, apoptosis-related cysteine peptidase |
| Family/Subfamily: | Protease , Cysteine C14 |
| Synonyms: | CASP5, CASP-5, Caspase 5, Caspase-5, ICE(rel)III, ICEREL-III, ICE(rel)-III, Ich-3, Protease TY, ICH3, Protease ICH-3, TY protease |
| Target Sequences: | NM_004347 NP_004338.3 P51878 |
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CASP5 / Caspase 5
(54)
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(41)
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(3)
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(19)
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aa145-327
(8)
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(4)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(2)
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(1)
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(4)
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(7)
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(2)
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(3)
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Purified
(1)
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$440
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa102-151) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
Sandwich
96-Well Strip Plate
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$764
E. coli
His, N-Terminal
47.7 kDa
50 µg/$419
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
0.1 mg/$460
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (80-160 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (290-370 aa, C-terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (p20, Cleaved-Asp121) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (p10, Cleaved-Ser331) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa312-361) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CASP5 / Caspase 5 Mouse anti-Human Monoclonal (4F7) Antibody
Human
WB
Unconjugated
100 µg/$403
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa341-386) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (Asp121) Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa251-300) Antibody
Human
WB
Unconjugated
100 µl/$424
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa145-327) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa145-327) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$325; 200 µl/$375; 500 µl/$539; 1 ml/$632; 2 ml/$867; 5 ml/$1,439
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