CASP4 / Caspase 4

caspase 4, apoptosis-related cysteine peptidase

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease. The rodent homolog is known as Caspase 4 and Caspase 11.

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Products

ELISA Kits (22)

Type

Competitive EIA (1)

Custom (3)

Development Kit (1)

Sandwich (15)

Sandwich CLIA (2)

Target

CASP4 / Caspase 4 (22)

Reactivity

Human (8)

Mouse (5)

Rat (1)

Chicken (1)

Guinea pig (1)

Monkey (2)

Porcine (1)

Rabbit (1)

Sheep (1)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (3)

96-Well Microplate (1)

96-Well Strip Plate (17)

Antibody Pair and Standard (1)

Publications

No (22)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (2)

Plasma (10)

Serum (10)

Tissue Homogenates (4)

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Human CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F4932

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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Human CASP4 / Caspase 4 (Custom ELISA) ELISA Kit - LS-F18399

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Mouse CASP4 / Caspase 4 (Custom ELISA) ELISA Kit - LS-F18398

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Bovine CASP4 / Caspase 4 (Custom ELISA) ELISA Kit - LS-F18400

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F35938

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rabbit CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F42027

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

31.25 - 2000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Sheep CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F42029

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

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Porcine CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F42028

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F42006

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Chicken CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F42023

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

31.25 - 2000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F42025

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F42026

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Mouse CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F38263

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Rat CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F38592

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Mouse CASP4 / Caspase 4 (CLIA) ELISA Kit - LS-F30564

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

78.125 - 5000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human CASP4 / Caspase 4 (CLIA) ELISA Kit - LS-F29517

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

DevKit DuoPlus Human CASP4 / Caspase 4 ELISA Development Kit - LS-F71762

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,229; 1000 Wells/$1,826

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Mouse CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F56045

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.391 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F20971

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F26782

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Human CASP4 / Caspase 4 (Sandwich ELISA) ELISA Kit - LS-F26809

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Mouse CASP4 / Caspase 4 (Competitive EIA) ELISA Kit - LS-F28272

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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