CASP1 / Caspase 1

caspase 1, apoptosis-related cysteine peptidase

CASP1 / Caspase 1 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

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Products

Proteins (16)

Type

Over-Expression Lysate (7)

Recombinant (9)

Target

CASP1 / Caspase 1 (16)

Publications

No (16)

Tag

GST (1)

GST, N-terminus (1)

His (4)

His, N-Terminal (2)

Myc-DDK (Flag) (8)

Species

Human (9)

Mouse (1)

Pig (1)

Rat (2)

Source

293T Cells (4)

E. coli (6)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human CASP1 / Caspase 1 Protein (Recombinant GST) (Full Length) - LS-G27743

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.4 kDa

Price:

2 µg/$439

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Human CASP1 / Caspase 1 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G57985

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CASP1 / Caspase 1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66088

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.6 kDa

Price:

20 µg/$1,107

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Rat CASP1 / Caspase 1 Protein (Recombinant His, N-Terminal) - LS-G132743

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

21kDa

Price:

10 µg/$370; 50 µg/$922; 200 µg/$1,577; 100 µg/$1,345; 1 mg/$2,945; 500 µg/$2,397; 5 mg/$6,441; 2 mg/$3,436

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Mouse CASP1 / Caspase 1 Protein (Recombinant His, N-Terminal) (aa119-296) - LS-G14039

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

21.6 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human CASP1 / Caspase 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76883

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.7 kDa

Price:

20 µg/$150

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Human CASP1 / Caspase 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76884

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.7 kDa

Price:

20 µg/$150

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Human CASP1 / Caspase 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76886

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.6 kDa

Price:

20 µg/$150

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Human CASP1 / Caspase 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76887

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.8 kDa

Price:

20 µg/$150

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Human CASP1 / Caspase 1 Protein (Recombinant His) (aa120-297) - LS-G14037

Source:

E. coli

Tag:

His

Molecular Weight:

21.4 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Human CASP1 / Caspase 1 Protein (Recombinant His) (aa317-404) - LS-G14040

Source:

E. coli

Tag:

His

Molecular Weight:

11.8 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Pig CASP1 / Caspase 1 Protein (Recombinant His) (aa120-297) - LS-G14042

Source:

E. coli

Tag:

His

Molecular Weight:

21.4 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Rat CASP1 / Caspase 1 Protein (Recombinant His) (aa119-296) - LS-G14045

Source:

E. coli

Tag:

His

Molecular Weight:

21.5 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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CASP1 / Caspase 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118717

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.7 kDa

Price:

100 µg/$494

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CASP1 / Caspase 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108310

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.8 kDa

Price:

100 µg/$494

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CASP1 / Caspase 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108311

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.6 kDa

Price:

100 µg/$494

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