CASP1 / Caspase 1

caspase 1, apoptosis-related cysteine peptidase

CASP1 / Caspase 1 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms.

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Products

ELISA Kits (29)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Custom (3)

Development Kit (1)

Sandwich (20)

Sandwich CLIA (3)

Target

CASP1 / Caspase 1 (29)

Reactivity

Human (9)

Mouse (8)

Rat (8)

Chicken (1)

Dog (1)

Guinea pig (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Sheep (1)

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Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (3)

96-Well Microplate (6)

96-Well Strip Plate (19)

Antibody Pair and Standard (1)

Publications

No (28)

Yes (1)

Sample Type

Adherent Cell Cultures (2)

Ascites (1)

Cell Culture Supernatants (6)

Cell Lysates (6)

Cerebrospinal Fluid (1)

Plasma (16)

Saliva (1)

Serum (16)

Tissue Homogenates (9)

Urine (1)

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Human CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F11012

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Ascites, Cell Culture Supernatants, Cerebrospinal Fluid, Plasma, Saliva, Serum, Tissue Homogenates, Urine

Price:

1 Plate/$585

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Mouse/Human/Rat CASP1 / Caspase 1 (Cell-Based ELISA) ELISA Kit - LS-F1851

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

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Dog CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F18070

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Dog

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F4802

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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Mouse CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F9042

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

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Human CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F33114

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F23503

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Rat CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F23890

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse/Human/Rat Phospho-CASP1 / Caspase 1 (Ser376) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1384

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Rat CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F6716

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$750

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Rat CASP1 / Caspase 1 (Custom ELISA) ELISA Kit - LS-F18067

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Pig CASP1 / Caspase 1 (Custom ELISA) ELISA Kit - LS-F18068

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse CASP1 / Caspase 1 (Custom ELISA) ELISA Kit - LS-F18069

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human CASP1 / Caspase 1 (CLIA) ELISA Kit - LS-F29069

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

6.25 - 400 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F37809

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Chicken CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F41995

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F41996

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F41998

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F41997

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Sheep CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F41999

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

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Rat CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F33115

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F33112

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat CASP1 / Caspase 1 (CLIA) ELISA Kit - LS-F37539

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse CASP1 / Caspase 1 (CLIA) ELISA Kit - LS-F30533

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

12.5 - 800 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse CASP1 / Caspase 1 (Sandwich ELISA) ELISA Kit - LS-F74264

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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