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CARD8 / Cardinal / TUCAN

caspase recruitment domain family, member 8

Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD8. This protein interacts with DRAL, a p53-responsive protein implicated in the induction of apoptosis, and caspase-1 and its related proteins ICEBERG and pesudo-ICE. Although there are conflicting reports on whether CARD8 acts a pro- or anti-apoptotic protein, it has been suggested that it functions as an adaptor molecule regulating caspase-1 and NF-kB activation.

Gene Name: caspase recruitment domain family, member 8
Family/Subfamily: Apoptosis
Synonyms: CARD8, Apoptotic protein NDPP1, DAKAR, KIAA0955, NDPP, TUCAN, CARDINAL, DACAR, NDPP1
Target Sequences: NM_014959 NP_055774.2 Q9Y2G2

☰ Filters
Antibodies (26)
Proteins (5)
Over-Expression Lysate (2)
Primary (26)
Recombinant (3)
CARD8 / Cardinal / TUCAN (31)
Human (26)
Mouse (3)
Rat (2)
IHC (10)
IHC-Fr (2)
IHC-P (4)
WB (24)
Flo (2)
DB (1)
ELISA (3)
ICC (3)
IF (4)
IP (7)
Peptide-ELISA (1)
rabbit (23)
mouse (3)
Product Group
IHCPlus (1)
IgG (14)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (24)
2108C2a (1)
APC Conjugated (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (18)
aa20-69 (4)
C-Terminus (1)
aa1-200 (1)
aa125-146 (1)
No (31)
GST (1)
GST, N-terminus (2)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (3)
Purified (1)
CARD8 / Cardinal / TUCAN Antibody - Anti-CARD8 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
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CARD8 / Cardinal / TUCAN Mouse anti-Human Monoclonal Antibody
Human
Flo, ICC, IP, WB
Unconjugated
50 µg/$558
CARD8 / Cardinal / TUCAN Antibody - Formalin-fixed, paraffin-embedded tissue human colon microarray stained for TUCAN/CARD8 expression at 1:2000 using Polyclonal Antibody to TUCAN/CARD8. A-A2, successively higher magnifications of the microarray. A, low magnification over view. A1, differential TUCAN/CARD8 staining between tissue cores is observed. A2, Areas of intense TUCAN/CARD8 staining in a colon carcinoma tissue core. Hematoxylin Eosin counterstain.
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$386
CARD8 / Cardinal / TUCAN Antibody - Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-CARD8 mAb.
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CARD8 / Cardinal / TUCAN Mouse anti-Human Monoclonal (2108C2a) Antibody
Human
DB, Flo, ICC, IF, IP, WB
Unconjugated
100 µg/$486
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC
Unconjugated
100 µg/$331
CARD8 / Cardinal / TUCAN Antibody - Formalin-fixed, paraffin-embedded human colon tissue sections labeled for TUCAN using Polyclonal Antibody to TUCAN/CARD8 at 1:2000. Hematoxylin-Eosin counterstain. A, normal adjacent colonic epithelium. B, matched malignant colonic epithelium shown in a region of invasive cancer. A and B are from the same colon carcinoma patient.
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (aa125-146) Antibody
Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$386
CARD8 / Cardinal / TUCAN Antibody - Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (aa1-200) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Human
IHC, IP, WB
Unconjugated
50 µl/$393
Select
CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Human
IHC, IP, WB
Unconjugated
50 µl/$393
CARD8 / Cardinal / TUCAN Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CARD8 / Cardinal / TUCAN Antibody - Western blot of CARD8 pAb in extracts from K562 and Hela cells.
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
CARD8 / Cardinal / TUCAN Antibody - Western blot analysis of extracts of various cell lines, using CARD8 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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CARD8 / Cardinal / TUCAN Mouse anti-Human Polyclonal Antibody
Human
IF, WB
Unconjugated
50 µg/$705
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µg/$649
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Select
CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
Select
CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
Select
CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
Select
CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
CARD8 / Cardinal / TUCAN Antibody - Western blot analysis of CARD 8 expression in K562 (A); ES2 (B) whole cell lysates.
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
CARD8 / Cardinal / TUCAN Antibody - Western blot of Human Fetal spleen. CARD8 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (aa20-69) Antibody
Human
WB
Unconjugated
100 µl/$424
CARD8 / Cardinal / TUCAN Antibody - Western blot of Human Fetal spleen. CARD8 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (aa20-69) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
CARD8 / Cardinal / TUCAN Antibody - Western blot of Human Fetal spleen. CARD8 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
CARD8 / Cardinal / TUCAN Rabbit anti-Human Polyclonal (aa20-69) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 31 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).