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Carboxylesterase 1 / CES1

carboxylesterase 1

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.

Gene Name: carboxylesterase 1
Synonyms: CES1, ACAT, Brain carboxylesterase hBr1, Carboxylesterase 1, Carboxylesterase 2 (liver), CEH, CES1A1, CES1A2, Cocaine carboxylesterase, Egasyn, HMSE, Liver carboxylesterase 1, HCE-1, PCE-1, Retinyl ester hydrolase, TGH, Triacylglycerol hydrolase, REH, SES1, CE-1, Cholesteryl ester hydrolase, HMSE1, Serine esterase 1
Target Sequences: L07764 AAA16036.1 P23141

Publications (1)

1
The targeted histone deacetylase inhibitor tefinostat (CHR-2845) shows selective in vitro efficacy in monocytoid-lineage leukaemias. Zabkiewicz J, Gilmour M, Hills R, Vyas P, Bone E, Davidson A, Burnett A, Knapper S. Oncotarget. 2016 7:16650-62. (WB; Human) [Full Text Article] [PubMed:26934551] [PMC:PMC4941341]

☰ Filters
Antibodies (59)
Proteins (15)
ELISA Kits (4)
Over-Expression Lysate (6)
Primary (59)
Recombinant (9)
Sandwich (4)
Carboxylesterase 1 / CES1 (78)
Human (40)
Mouse (13)
Rat (15)
Bovine (6)
Chimpanzee (3)
Dog (6)
Gibbon (6)
Guinea pig (6)
Monkey (3)
Pig (6)
IHC (10)
IHC-P (5)
WB (55)
ELISA (13)
IP (1)
Peptide-ELISA (2)
rabbit (56)
mouse (2)
goat (1)
Product Group
IHCPlus (3)
IgG (30)
IgG2b (1)
monoclonal mc (1)
polyclonal pc (58)
11n45 (1)
96-Well Microplate (1)
96-Well Strip Plate (2)
APC (3)
APC Conjugated (4)
Biotin Conjugated (9)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (7)
HRP Conjugated (9)
Liquid (3)
Lyophilized (3)
PE Conjugated (4)
Unconjugated (20)
aa18-299 (8)
aa19-300 (8)
C-Terminus (4)
aa33-82 (4)
aa19-563 (1)
aa533-544 (1)
No (78)
Cell Culture Supernatants (2)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (3)
Serum (4)
Tissue Homogenates (2)
6His, C-terminus (2)
GST (1)
His, N-Terminal (2)
His-T7, N-terminus (1)
Myc-DDK (Flag) (9)
Human (10)
Mouse (1)
Rat (1)
293T Cells (3)
E. coli (3)
HEK 293 Cells (6)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (2)
Carboxylesterase 1 / CES1 Antibody - Anti-CES1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Carboxylesterase 1 / CES1 Goat anti-Human Polyclonal (aa533-544) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Carboxylesterase 1 / CES1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$783
Carboxylesterase 1 / CES1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
28.67 - 7000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$635
Carboxylesterase 1 / CES1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
Carboxylesterase 1 / CES1 Protein - Recombinant Carboxylesterase 1 By SDS-PAGE
Select
E. coli
His, N-Terminal
34.1 kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 1 mg/$2,016; 5 mg/$3,151; 2 mg/$2,204
Carboxylesterase 1 / CES1 Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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Carboxylesterase 1 / CES1 Rabbit anti-Pig Polyclonal (Liquid) Antibody
Pig
ELISA, WB
Unconjugated, Liquid
25 µl/$304
Carboxylesterase 1 / CES1 Antibody - IHC analysis of CES1 using anti-CES1 antibody. CES1 was detected in paraffin-embedded section of rat lung tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-CES1 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Carboxylesterase 1 / CES1 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
61.05kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
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Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Carboxylesterase 1 / CES1 Antibody - Immunohistochemical analysis of CES1 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
Carboxylesterase 1 / CES1 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Carboxylesterase 1 / CES1 Antibody - Western Blot of Rabbit anti-Esterase Antibody Peroxidase Conjugated. Lane 1: Esterase (Porcine Liver). Load: 50 ng per lane. Primary antibody: Rabbit anti-Esterase Antibody Peroxidase Conjugated at 1:1,000 overnight at 4°C. Secondary antibody: n/a.
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Carboxylesterase 1 / CES1 Rabbit anti-Pig Polyclonal (Lyophilized) (HRP) Antibody
Pig
ELISA, IHC, WB
HRP Conjugated, Lyophilized
100 µg/$552
Carboxylesterase 1 / CES1 Antibody - Western Blot of rabbit anti-Esterase Antibody Peroxidase Conjugated. Lane 1: Esterase (Porcine Liver). Load: 50 ng per lane. Primary antibody: Rabbit anti-Esterase Antibody Peroxidase Conjugated at 1:1,000 overnight at 4°C. Secondary antibody: n/a. Block: MB-070 for 30 min at RT. Predicted/Observed size: 62 kDa, 55 kDa for Esterase.
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Carboxylesterase 1 / CES1 Rabbit anti-Pig Polyclonal (Liquid) (HRP) Antibody
Pig
ELISA, IHC, WB
HRP Conjugated, Liquid
25 µl/$304
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Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$830
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Carboxylesterase 1 / CES1 Mouse anti-Human Monoclonal (aa19-563) (11n45) Antibody
Human
IP, WB
Unconjugated
100 µg/$896
Select
Carboxylesterase 1 / CES1 Rabbit anti-Pig Polyclonal (Lyophilized) Antibody
Pig
ELISA, WB
Unconjugated, Lyophilized
100 µg/$567
Carboxylesterase 1 / CES1 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using CES1 Antibody at dilution of 1:100
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Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Carboxylesterase 1 / CES1 Antibody
Select
Carboxylesterase 1 / CES1 Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
Select
Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
Carboxylesterase 1 / CES1 Antibody - Western Blot of Rabbit anti-Esterase Antibody Biotin Conjugated. Lane 1: Esterase (Porcine Liver). Load: 50 ng per lane. Primary antibody: Rabbit anti-Esterase Antibody Biotin Conjugated at 1:1,000 overnight at 4°C. Secondary antibody: HRP Streptavidin secondary antibody at 1:40,000 for 30 min at RT.
Select
Carboxylesterase 1 / CES1 Rabbit anti-Pig Polyclonal (Lyophilized) (Biotin) Antibody
Pig
ELISA, WB
Biotin Conjugated, Lyophilized
100 µg/$552
Carboxylesterase 1 / CES1 Antibody - Western Blot of rabbit anti-Esterase Antibody Biotin Conjugated. Lane 1: Esterase (Porcine Liver). Load: 50 ng per lane. Primary antibody: Rabbit anti-Esterase Antibody Biotin Conjugated at 1:1,000 overnight at 4°C. Secondary antibody: HRP Streptavidin secondary antibody at 1:40,000 for 30 min at RT. Block: MB-070 for 30 min at RT. Predicted/Observed size: 62 kDa, 55 kDa for Esterase.
Select
Carboxylesterase 1 / CES1 Rabbit anti-Pig Polyclonal (Liquid) (Biotin) Antibody
Pig
ELISA, WB
Biotin Conjugated, Liquid
25 µl/$304
Carboxylesterase 1 / CES1 Antibody - Western blot of Carboxylesterase 1 / CES1 antibody.
Select
Carboxylesterase 1 / CES1 Rabbit anti-Human Polyclonal (aa18-299) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Viewing 1-25 of 78 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).