CAPNS1 / CAPN4

calpain, small subunit 1

CAPNS1 / CAPN4 is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.

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Products

Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

CAPNS1 / CAPN4 (9)

Publications

No (9)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-GST (1)

His-SUMO (1)

Myc-DDK (Flag) (4)

Species

Human (8)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human CAPNS1 / CAPN4 Protein (Recombinant His) - LS-G2895

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human CAPNS1 / CAPN4 Protein (Recombinant GST, N-terminus) (aa172-260) - LS-G57976

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CAPNS1 / CAPN4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65120

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.1 kDa

Price:

20 µg/$1,107

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Human CAPNS1 / CAPN4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65124

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.1 kDa

Price:

20 µg/$1,107

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Human CAPNS1 / CAPN4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74906

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.1 kDa

Price:

20 µg/$150

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CAPNS1 / CAPN4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118420

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.1 kDa

Price:

100 µg/$494

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Human CAPNS1 / CAPN4 Protein (Recombinant GST) (Full Length) - LS-G27736

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

54.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CAPNS1 / CAPN4 Protein (Recombinant His-GST) (aa1-268) - LS-G25575

Source:

E. coli

Tag:

His-GST

Molecular Weight:

58.3 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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Human CAPNS1 / CAPN4 Protein (Recombinant His-SUMO) (Full Length) - LS-G20558

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

44.3 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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