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CAPN1 / Calpain 1

calpain 1, (mu/I) large subunit

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene.

Gene Name: calpain 1, (mu/I) large subunit
Family/Subfamily: Protease , Cysteine C2
Synonyms: CAPN1, Calpain i, Calpain mu-type, Calpain, large polypeptide L1, Calpain-1 catalytic subunit, Calpain 1, Calpain-1 large subunit, CANP, CANP1, Mu CANP, Mu-calpain, Mu-type calpain, MuCANP, Micromolar-calpain, MuCL, CANP 1, CANPL1
Target Sequences: BC008751 AAH08751.1 P07384

Publications (1)

1
Calpain-2 as a therapeutic target in repeated concussion-induced neuropathy and behavioral impairment. Yubin Wang, Yan Liu, Amy Nham, Arash Sherbaf, Diana Quach, Emad Yahya, Davis Ranburger, Xiaoning Bi, Michel Baudry. Science advances. 2020 July;6: [Full Text Article] [PubMed:32937436] [PMC:PMC7458466] Related Antibodies: LS-B4768.

☰ Filters
Products
Proteins (14)
Over-Expression Lysate (2)
Recombinant (12)
CAPN1 / Calpain 1 (14)
No (14)
6His, N-terminus (2)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His (6)
His, N-Terminal (2)
Myc-DDK (Flag) (2)
Human (6)
Mouse (3)
Rat (4)
293T Cells (1)
E. coli (11)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
CAPN1 / Calpain 1 Protein
Select
E. coli
6His, N-terminus
85.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
CAPN1 / Calpain 1 Protein - Recombinant Calpain 1, Large Subunit By SDS-PAGE
Select
E. coli
6His, N-terminus
31.8 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
CAPN1 / Calpain 1 Protein - Recombinant Calpain 1, Large Subunit By SDS-PAGE
Select
E. coli
His
30.7 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
CAPN1 / Calpain 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CAPN1 / Calpain 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
81.7 kDa
20 µg/$150
CAPN1 / Calpain 1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
81.7 kDa
100 µg/$494
CAPN1 / Calpain 1 Protein
Select
E. coli
GST, N-terminus + His, C-terminus
109.7 kDa
50 µg/$419
CAPN1 / Calpain 1 Protein - Active Calpain 1, Large Subunit (CAPN1) by WB
Select
E. coli
His, N-Terminal
35kDa
10 µg/$327; 50 µg/$727; 200 µg/$1,332; 100 µg/$1,126; 1 mg/$2,605; 500 µg/$2,102; 5 mg/$5,076; 2 mg/$2,797
CAPN1 / Calpain 1 Protein
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E. coli
His
86.15 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
CAPN1 / Calpain 1 Protein - Recombinant Calpain 1, Large Subunit By SDS-PAGE
Select
E. coli
His
21.4 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
CAPN1 / Calpain 1 Protein - Recombinant Calpain 1, Large Subunit By SDS-PAGE
Select
E. coli
His
37.5 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
Select
E. coli
His
37.5 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
CAPN1 / Calpain 1 Protein - Recombinant Calpain 1, Large Subunit By SDS-PAGE
Select
E. coli
His
33.7 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
CAPN1 / Calpain 1 Protein - Active Calpain 1, Large Subunit (CAPN1) by WB
Select
E. coli
His, N-Terminal
33kDa
10 µg/$327; 50 µg/$727; 200 µg/$1,332; 100 µg/$1,126; 1 mg/$2,605; 500 µg/$2,102; 5 mg/$5,076; 2 mg/$2,797
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).