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CAMK2N2 / CAMKIIN is a protein that is highly similar to the rat CaM-KII inhibitory protein, an inhibitor of calcium/calmodulin-dependent protein kinase II (CAMKII). CAMKII regulates numerous physiological functions, including neuronal synaptic plasticity through the phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate (AMPA) receptors. Studies of the similar protein in rat suggest that this protein may function as a negative regulator of CaM-KII and may act to inhibit the phosphorylation of AMPA receptors.
Gene Name: | calcium/calmodulin-dependent protein kinase II inhibitor 2 |
Synonyms: | CAMK2N2, CaM-KII inhibitory protein, CAMKIIN, CAM-KIIN |
Target Sequences: | NP_150284.1 Q96S95 |
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