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Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta.
Gene Name: | calcium/calmodulin-dependent protein kinase ID |
Family/Subfamily: | Protein Kinase , CAMK1 |
Synonyms: | CAMK1D, CaM kinase ID, CaMKI-like protein kinase, CaMKID, CKLiK, CaM kinase I delta, CaM-K1, CaMKI delta, CaM-KI delta, CaMKI-like kinase |
Target Sequences: | NM_020397 NP_065130.1 Q8IU85 |
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