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CALCR / Calcitonin Receptor

calcitonin receptor

The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes.

Gene Name: calcitonin receptor
Family/Subfamily: GPCR , Calcitonin
Synonyms: CALCR, Calcitonin receptor, CRT, CT-R, CTR, CT receptor
Target Sequences: NM_001742 NP_001733.1 P30988

Publications (2)

1
Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis. Santiago L, Menaa C, Arias M, Martin P, Jaime-Sánchez P, Metkar S, Comas L, Erill N, Gonzalez-Rumayor V, Esser E, Galvez EM, Raja S, Simon MM, Sprague SM, Gabay C, Martinez-Lostao L, Pardo J, Froelich CJ. Arthritis and rheumatism. 2017 February;69:320-334. (Rat) [Full Text Article] [PubMed:27598995]
2
Inhibition of miR-29 Activity in the Myeloid Lineage Increases Response to Calcitonin and Trabecular Bone Volume in Mice. Bongjin Shin, Henry C Hrdlicka, Anne M Delany, Sun-Kyeong Lee. Endocrinology. 2021 October;162: [Full Text Article] [PubMed:34192317] [PMC:PMC8328098] Related Antibodies: LS-C374476.

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Products
Proteins (11)
Over-Expression Lysate (6)
Recombinant (5)
CALCR / Calcitonin Receptor (11)
SDS-PAGE (1)
No (11)
GST (1)
GST, N-terminus (1)
His-T7 (2)
Human IgG1 Fc, N-terminus (1)
Myc-DDK (Flag) (6)
Human (6)
Mouse (1)
Rat (1)
293T Cells (3)
E. coli (2)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (1)
CALCR / Calcitonin Receptor Protein
Select
HEK 293 Cells
Human IgG1 Fc, N-terminus
SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant human CALCR consists 390 amino acids and predicts a molecular mass of 43.9 kDa.
100 µg/$480
CALCR / Calcitonin Receptor Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CALCR / Calcitonin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
59.2 kDa
20 µg/$150
CALCR / Calcitonin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.34 kDa
20 µg/$150
CALCR / Calcitonin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.34 kDa
20 µg/$150
CALCR / Calcitonin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
59.2 kDa
100 µg/$494
CALCR / Calcitonin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.34 kDa
100 µg/$494
CALCR / Calcitonin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.34 kDa
100 µg/$494
CALCR / Calcitonin Receptor Protein - Recombinant Calcitonin Receptor By SDS-PAGE
Select
E. coli
His-T7
18.8 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
CALCR / Calcitonin Receptor Protein - Recombinant Calcitonin Receptor By SDS-PAGE
Select
E. coli
His-T7
17.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
CALCR / Calcitonin Receptor Protein - 12.5% SDS-PAGE of human CALCR stained with Coomassie Blue
Select
Wheat Germ Extract
GST
81.7 kDa
2 µg/$439
Viewing 1-11 of 11 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).