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The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes.
Gene Name: | calcitonin receptor |
Family/Subfamily: | GPCR , Calcitonin |
Synonyms: | CALCR, Calcitonin receptor, CRT, CT-R, CTR, CT receptor |
Target Sequences: | NM_001742 NP_001733.1 P30988 |
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