CALCOCO1 / CoCoa

calcium binding and coiled-coil domain 1

Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions.

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Products

Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

CALCOCO1 / CoCoa (6)

Publications

No (6)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CALCOCO1 / CoCoa Protein (Recombinant GST) (Full Length) - LS-G34769

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

103.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CALCOCO1 / CoCoa Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87383

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.4 kDa

Price:

20 µg/$150

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Human CALCOCO1 / CoCoa Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87384

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.2 kDa

Price:

20 µg/$150

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Human CALCOCO1 / CoCoa Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70542

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.2 kDa

Price:

20 µg/$1,107

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CALCOCO1 / CoCoa Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126153

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.4 kDa

Price:

100 µg/$494

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CALCOCO1 / CoCoa Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110889

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.2 kDa

Price:

100 µg/$494

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