CACNB4

calcium channel, voltage-dependent, beta 4 subunit

CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Multiple transcript variants encoding different isoforms have been found for this gene.

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Proteins (10)

Type

Over-Expression Lysate (8)

Recombinant (2)

Target

CACNB4 (10)

Publications

No (10)

Tag

GST (1)

Myc-DDK (Flag) (9)

Species

Human (6)

Source

293T Cells (4)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CACNB4 Protein (Recombinant GST) (Full Length) - LS-G27713

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

84.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CACNB4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67335

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58 kDa

Price:

20 µg/$1,107

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CACNB4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99125

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58 kDa

Price:

100 µg/$494

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Human CACNB4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79569

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

58 kDa

Price:

20 µg/$150

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Human CACNB4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79571

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.5 kDa

Price:

20 µg/$215

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Human CACNB4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79570

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.2 kDa

Price:

20 µg/$215

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Human CACNB4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79572

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.2 kDa

Price:

20 µg/$150

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CACNB4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126833

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.2 kDa

Price:

100 µg/$494

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CACNB4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122144

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.2 kDa

Price:

100 µg/$710

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CACNB4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122146

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.5 kDa

Price:

100 µg/$710

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