CACNA1I / Cav3.3

calcium channel, voltage-dependent, T type, alpha 1I subunit

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. Isoform alpha-1I gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes. Gates in voltage ranges similar to, but higher than alpha 1G or alpha 1H.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

CACNA1I / Cav3.3 (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human CACNA1I / Cav3.3 Protein (Recombinant GST, N-terminus) (aa233-331) - LS-G60934

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human CACNA1I / Cav3.3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91479

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

244.9 kDa

Price:

20 µg/$215

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CACNA1I / Cav3.3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110773

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

244.9 kDa

Price:

100 µg/$710

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