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C6orf134 / ATAT1
alpha tubulin acetyltransferase 1
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Required for normal sperm flagellar function. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
| Gene Name: | alpha tubulin acetyltransferase 1 |
| Synonyms: | ATAT1, Alpha-TAT, Em:AB023049.7, MEC17, Nbla00487, C6orf134 |
| Target Sequences: | NM_024909 NP_079185.2 Q5SQI0 |
Publications (1)
1
Non-enzymatic Activity of the a-Tubulin Acetyltransferase aTAT Limits Synaptic Bouton Growth in Neurons. Courtney E Coombes, Harriet A J Saunders, Anirudh G Mannava, Dena M Johnson-Schlitz, Taylor A Reid, Sneha Parmar, Mark McClellan, Connie Yan, Stephen L Rogers, Jay Z Parrish, Michael Wagenbach, Linda Wordeman, Jill Wildonger, Melissa K Gardner. Current biology : CB. 2020 February;30:610-623e5. [Full Text Article]
[PubMed:31928876]
[PMC:PMC7047862]
Related Antibodies: LS-C116215.
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Antibodies
(21)
Type
Primary
(21)
Target
C6orf134 / ATAT1
(21)
Reactivity
Human
(20)
Mouse
(13)
Rat
(14)
Bat
(6)
Bovine
(6)
Chimpanzee
(6)
Dog
(9)
Gibbon
(12)
Guinea pig
(9)
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(12)
Monkey
(12)
Orangutan
(9)
Pig
(9)
Rabbit
(6)
Application
IHC
(1)
IHC-P
(1)
WB
(18)
ELISA
(1)
IF
(1)
Peptide-ELISA
(1)
Host
rabbit
(21)
Isotype
IgG
(13)
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polyclonal pc
(21)
Format
Biotin Conjugated
(5)
FITC Conjugated
(5)
HRP Conjugated
(5)
Unconjugated
(6)
Epitope
N-Terminus
(8)
aa108-157
(4)
aa251-300
(4)
Publications
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(20)
Yes
(1)
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Orangutan, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$442
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Orangutan, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$442
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Orangutan, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$442
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (aa108-157) Antibody
Human
WB
Unconjugated
100 µl/$424
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (aa108-157) (HRP) Antibody
Rabbit, Mouse, Dog, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (aa108-157) (Biotin) Antibody
Rabbit, Mouse, Dog, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (aa108-157) (FITC) Antibody
Rabbit, Mouse, Dog, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
C6orf134 / ATAT1 Rabbit anti-Rat Polyclonal (aa251-300) Antibody
Rat
WB
Unconjugated
100 µl/$424
C6orf134 / ATAT1 Rabbit anti-Rat Polyclonal (aa251-300) (HRP) Antibody
Mouse, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
C6orf134 / ATAT1 Rabbit anti-Rat Polyclonal (aa251-300) (Biotin) Antibody
Mouse, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
C6orf134 / ATAT1 Rabbit anti-Rat Polyclonal (aa251-300) (FITC) Antibody
Mouse, Guinea pig, Rat, Pig, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
C6orf134 / ATAT1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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product results
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