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C5AR1 / CD88 / C5a Receptor
complement component 5a receptor 1
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
| Gene Name: | complement component 5a receptor 1 |
| Family/Subfamily: | GPCR , Anaphylatoxin |
| Synonyms: | C5AR1, C5A, C5a-R, C5a ligand, C5a receptor, CD88, C5a anaphylatoxin receptor, C5AR, C5R1, CD88 antigen |
| Target Sequences: | NM_001736 NP_001727.1 P21730 |
Publications (2)
1
A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an Anti-C5aR1 Antibody and C5 Small Interfering RNA. Mehta G, Scheinman RI, Holers VM, Banda NK. Journal of immunology (Baltimore, Md. : 1950). 2015 194:5446-54. (Flo; Mouse)
[Full Text Article]
[PubMed:25917104]
[PMC:PMC4433857]
Related Antibodies: LS-C209596.
2
Deletion of Biliverdin Reductase A in Myeloid Cells Promotes Chemokine Expression and Chemotaxis in Part via a Complement C5a--C5aR1 Pathway. Kavita Bisht, Giacomo Canesin, Tasneem Cheytan, Mailin Li, Zsuzsanna Nemeth, Eva Csizmadia, Trent M Woodruff, David E Stec, Andrew C Bulmer, Leo E Otterbein, Barbara Wegiel. Journal of immunology (Baltimore, Md. : 1950). 2019 May;202:2982-2990. [Full Text Article]
[PubMed:30952817]
[PMC:PMC6504595]
Related Antibodies: LS-B5229.
☰ Filters
Products
ELISA Kits
(3)
Type
Cell-Based
(1)
Cell-Based Phosphorylation
(1)
Sandwich
(1)
Target
C5AR1 / CD88 / C5a Receptor
(3)
Reactivity
Human
(2)
Mouse
(1)
Format
96-Well Microplate
(2)
96-Well Strip Plate
(1)
Publications
No
(3)
Sample Type
Adherent Cell Cultures
(2)
Cell Lysates
(1)
Tissue Homogenates
(1)
Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
Sandwich
96-Well Strip Plate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$715
Cell-Based Phosphorylation
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$641
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