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C3AR / C3a Receptor

complement component 3a receptor 1

The C3a Anaphylatoxin Receptor mediates the effects of the inflammatory mediator anaphylatoxin C3a, which is released during complement activation. This receptor stimulates chemotaxis, granule enzyme release, and superoxide anion production. It also regulates glial cell activation, may be involved in the pathogenesis of asthma, and may promote cell repair.

Gene Name: complement component 3a receptor 1
Family/Subfamily: GPCR , Anaphylatoxin
Synonyms: C3AR1, AZ3B, C3AR, C3R1, C3a receptor, C3a-R, HNFAG09, Anaphylatoxin c3a receptor, C3a anaphylatoxin receptor
Target Sequences: NM_004054 NP_004045.1 Q16581

Publications (1)

1
C3a receptor blockade protects podocytes from injury in diabetic nephropathy. Marina Morigi, Luca Perico, Daniela Corna, Monica Locatelli, Paola Cassis, Claudia Elisa Carminati, Silvia Bolognini, Carlamaria Zoja, Giuseppe Remuzzi, Ariela Benigni, Simona Buelli. JCI insight. 2020 Mar;5:e131849. [Full Text Article] [PubMed:32161193] [PMC:PMC7141402] Related Antibodies: LS-C382362.

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Proteins (4)
Over-Expression Lysate (2)
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C3AR / C3a Receptor (4)
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Alzheimer's Disease (4)
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Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
C3AR / C3a Receptor Protein - 12.5% SDS-PAGE of human C3AR1 stained with Coomassie Blue
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Wheat Germ Extract
GST
80.3 kDa
2 µg/$439
C3AR / C3a Receptor Protein - Purified recombinant protein C3AR1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
53.7 kDa
20 µg/$1,107
C3AR / C3a Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
53.7 kDa
100 µg/$494
C3AR / C3a Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
53.7 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).